(Q71058150)

English

Protective effect of O6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs

scientific article published on 01 February 1996

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scholarly article

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Europe PubMed Central

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15 October 2019

Protective effect of O6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8621235%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

author name string

I Preuss

1

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15 October 2019

R Thust

2

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15 October 2019

B Kaina

3

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15 October 2019

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1 February 1996

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15 October 2019

International Journal of Cancer

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15 October 2019

65

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15 October 2019

4

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15 October 2019

506-512

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15 October 2019

Cell specific differences in O6-methylguanine-DNA methyltransferase activity and removal of O6-methylguanine in rat pulmonary cells

1 reference

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21 January 2018

Association between growth stimulation by phenobarbital and expression of cytochromes P450 1A1, 1A2, 2B1/2 and 3A1 in hepatic hyperplastic nodules in male F344 rats

1 reference

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21 January 2018

Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents

1 reference

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21 January 2018

Some new congeners of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) synthesis of bifunctional analogs and water soluble derivatives and preliminary evaluation of their chemotherapeutic potential

1 reference

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21 January 2018

DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds

1 reference

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21 January 2018

O6 alkylguanine-DNA alkyltransferase activity in human myeloid cells

1 reference

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21 January 2018

Specific DNA repair mechanisms may protect some human tumor cells from DNA interstrand crosslinking by chloroethylnitrosoureas but not from crosslinking by other anti-tumor alkylating agents.

1 reference

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21 January 2018

Deoxyribonucleic acid crosslinking by 4-hydroperoxycyclophosphamide in cyclophosphamide-sensitive and -resistant L1210 cells

1 reference

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21 January 2018

Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines

1 reference

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21 January 2018

Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

1 reference

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21 January 2018

Self-destruction and tolerance in resistance of mammalian cells to alkylation damage

1 reference

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21 January 2018

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

1 reference

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21 January 2018

DNA alkylation by the haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removal

1 reference

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21 January 2018

O6-methylguanine-DNA methyltransferase activity in breast and brain tumors.

1 reference

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21 January 2018

On the quantitative relationship between O6-methylguanine residues in genomic DNA and production of sister-chromatid exchanges, mutations and lethal events in a Mer- human tumor cell line

1 reference

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21 January 2018

Cross-linking of DNA induced by chloroethyinitrosourea is prevented by O6-methyiguanine-DNA methyttransferase

1 reference

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21 January 2018

Clinical antitumor activity and toxicity of streptozotocin (NSC-85998)

1 reference

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21 January 2018

Comparative study on the influence of two 2-chloroethylnitrosoureas with different carbamoylating potential towards glutathione and glutathione-related enzymes in different organs of the rat.

1 reference

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21 January 2018

Differential Giemsa staining of sister chromatids after extraction with acids

1 reference

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21 January 2018

Inactivation of O6-alkylguanine-DNA alkyltransferase in HeLa cells by cisplatin.

1 reference

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21 January 2018

Identifiers

10.1002/(SICI)1097-0215(19960208)65:4<506::AID-IJC19>3.0.CO;2-7

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8621235%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

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