(Q71059029)

English

The common I172N mutation causes conformational change of cytochrome P450c21 revealed by systematic mutation, kinetic, and structural studies

scientific article published on 01 February 1996

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scholarly article

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15 October 2019

The common I172N mutation causes conformational change of cytochrome P450c21 revealed by systematic mutation, kinetic, and structural studies (English)

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15 October 2019

author name string

L C Hsu

1

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15 October 2019

N C Hsu

2

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15 October 2019

J A Guzova

3

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15 October 2019

V M Guzov

4

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15 October 2019

S F Chang

5

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15 October 2019

B C Chung

6

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publication date

1 February 1996

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15 October 2019

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5

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Journal of Biological Chemistry

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15 October 2019

271

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15 October 2019

6

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15 October 2019

3306-3310

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15 October 2019

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Oxygen activation by cytochrome P-450.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Molecular biology of steroid hormone synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Signals for the incorporation and orientation of cytochrome P450 in the endoplasmic reticulum membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Determination of the membrane topology of the phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4 using site-specific antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Identification of the membrane anchor of microsomal rat liver cytochrome P-450.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Determination of membrane-bound fragments of cytochrome P-450 2B4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

The molecular genetics of 21-hydroxylase deficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Structure of human steroid 21-hydroxylase genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Structure and expression of the CYP21 (P450c21, steroid 21-hydroxylase) gene with respect to its deficiency.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Expression of human 21-hydroxylase (P450c21) in bacterial and mammalian cells: a system to characterize normal and mutant enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Mutations of P450c21 (steroid 21-hydroxylase) at Cys428, Val281, and Ser268 result in complete, partial, or no loss of enzymatic activity, respectively

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Effects of individual mutations in the P-450(C21) pseudogene on the P-450(C21) activity and their distribution in the patient genomes of congenital steroid 21-hydroxylase deficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Disease expression and molecular genotype in congenital adrenal hyperplasia due to 21-hydroxylase deficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Mutation in the CYP21B gene (Ile-172----Asn) causes steroid 21-hydroxylase deficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Expression and functional study of wild-type and mutant human cytochrome P450c21 in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Amplification of P450c21 expression in cultured mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

14 Expression of mammalian cytochrome P450 enzymes using yeast-based vectors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Expression of rat liver cytochrome P-450MC cDNA in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

The mitochondrial chaperonin hsp60 is required for its own assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Purification and properties of cytochrome P-45011β from adrenocortical mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Dynamic structures of adrenocortical cytochrome P-450 in proteoliposomes and microsomes: protein rotation study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Conjugation of ubiquitin to denatured hemoglobin is proportional to the rate of hemoglobin degradation in HeLa cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Bacteriophage lambda cro mutations: effects on activity and intracellular degradation

1 reference

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21 January 2018

The biology and enzymology of eukaryotic protein acylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Structure of a bovine gene for P-450c21 (steroid 21-hydroxylase) defines a novel cytochrome P-450 gene family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Nucleotide sequence analysis of murine 21-hydroxylase genes: mutations affecting gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.6.3306

21 January 2018

Identifiers

10.1074/JBC.271.6.3306

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8621735%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8621735%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

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