(Q71070052)

English

Posttranslational regulation of a Leishmania HEXXH metalloprotease (gp63). The effects of site-specific mutagenesis of catalytic, zinc binding, N-glycosylation, and glycosyl phosphatidylinositol addition sites on N-terminal end cleavage, intracellul

scientific article published on 01 April 1996

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scholarly article

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15 October 2019

Posttranslational regulation of a Leishmania HEXXH metalloprotease (gp63). The effects of site-specific mutagenesis of catalytic, zinc binding, N-glycosylation, and glycosyl phosphatidylinositol addition sites on N-terminal end cleavage, intracellular stability, and extracellular exit (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8626468%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

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B S McGwire

1

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15 October 2019

K P Chang

2

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15 October 2019

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1 April 1996

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15 October 2019

Journal of Biological Chemistry

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8626468%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

271

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15 October 2019

14

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15 October 2019

7903-7909

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8626468%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

Evolutionary families of metallopeptidases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Leishmanolysin: surface metalloproteinase of Leishmania

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Molecular determinants of Leishmania virulence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Monoclonal antibody affinity purification of a Leishmania membrane glycoprotein and its inhibition of leishmania-macrophage binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Extrachromosomal genetic complementation of surface metalloproteinase (gp63)-deficient Leishmania increases their binding to macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Genetic rescue of surface metalloproteinase (gp63)-deficiency in Leishmania amazonensis variants increases their infection of macrophages at the early phase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Molecular cloning of the major surface antigen of leishmania

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Heterogeneity of the genes encoding the major surface glycoprotein of Leishmania donovani

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Leishmania gp63 molecule implicated in cellular adhesion lacks an Arg-Gly-Asp sequence.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Structurally distinct genes for the surface protease of Leishmania mexicana are developmentally regulated

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Genes encoding the major surface glycoprotein in Leishmania are tandemly linked at a single chromosomal locus and are constitutively transcribed

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Sequence heterogeneity and polymorphic gene arrangements of the Leishmania guyanensis gp63 genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Recombinant Leishmania surface glycoprotein GP63 is secreted in the baculovirus expression system as a latent metalloproteinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

The structure and biosynthesis of glycosyl phosphatidylinositol protein anchors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

A glycosylphosphatidylinositol (GPI)-negative phenotype produced in Leishmania major by GPI phospholipase C from Trypanosoma brucei: topography of two GPI pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Selectivity of the cleavage/attachment site of phosphatidylinositol-glycan-anchored membrane proteins determined by site-specific mutagenesis at Asp-484 of placental alkaline phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

N-glycosylation as a biochemical basis for virulence in Leishmania mexicana amazonensis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in Chinese hamster ovary cells and a murine cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Role of glycosylation in transport and enzymic activity of neutral endopeptidase-24.11.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

An investigation into the significance of the N-linked oligosaccharides of Leishmania gp63.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Identification by extrachromosomal amplification and overexpression of a zeta-crystallin/NADPH-oxidoreductase homologue constitutively expressed in Leishmania spp.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Exploration of the catalytic site of endopeptidase 24.11 by site-directed mutagenesis. Histidine residues 583 and 587 are essential for catalysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

An unusual active site identified in a family of zinc metalloendopeptidases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Changing the spacing between metal-binding motifs decreases stability and transforming activity of the human papillomavirus type 18 E7 oncoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Biosynthesis of a phosphatidylinositol-glycan-linked membrane protein: signals for posttranslational processing of the Ly-6E antigen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Tunicamycin-resistant Leishmania mexicana amazonensis: expression of virulence associated with an increased activity of N-acetylglucosaminyltransferase and amplification of its presumptive gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Conformational implications of asparagine-linked glycosylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Mutational and functional analysis of the Leishmania surface metalloproteinase GP63: similarities to matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.14.7903

21 January 2018

Identifiers

10.1074/JBC.271.14.7903

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8626468%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8626468%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

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