(Q71283715)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

title

RPR 101821, a new potent cholesterol-lowering agent: inhibition of squalene synthase and 7-dehydrocholesterol reductase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

1 reference

D Amin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

R Z Rutledge

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

S J Needle

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

D J Hele

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

K Neuenswander

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

R C Bush

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

G E Bilder

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

M H Perrone

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

publication date

1 January 1996

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

Naunyn-Schmiedeberg's Archives of Pharmacology

17 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

volume

353

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

page(s)

233-240

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/bf00168762

17 October 2019

exact match

0 references

cites work

Isoprenyl phosphinylformates: new inhibitors of squalene synthetase

1 reference

12 December 2020

Regulation of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA contents in human hepatoma cell line Hep G2 by distinct classes of mevalonate-derived metabolites

1 reference

12 December 2020

Enzyme inhibition during the conversion of squalene to cholesterol

1 reference

12 December 2020

Effects of ML-236B on cholesterol metabolism in mice and rats: lack of hypocholesterolemic activity in normal animals

1 reference

12 December 2020

Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme.

1 reference

12 December 2020

Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells

1 reference

12 December 2020

Combined drug therapy--cholestyramine and compactin--for familial hypercholesterolemia

1 reference

12 December 2020

Bisphosphonates used for the treatment of bone disorders inhibit squalene synthase and cholesterol biosynthesis.

1 reference

12 December 2020

Reproducing abnormal cholesterol biosynthesis as seen in the Smith-Lemli-Opitz syndrome by inhibiting the conversion of 7-dehydrocholesterol to cholesterol in rats

1 reference

12 December 2020

Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Gene Expression by Sterols and Nonsterols in Rat Liver

1 reference

12 December 2020

Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

12 December 2020

Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo

1 reference

12 December 2020

HMG-CoA reductase inhibitors for treatment of hypercholesterolemia

1 reference

12 December 2020

Operator constitutive mutation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter abolishes protein binding to sterol regulatory element

1 reference

12 December 2020

Studies of cholesterol biosynthesis. I. The identification of desmosterol in serum and tissues of animals and man treated with MER-29

1 reference

12 December 2020

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent

1 reference

12 December 2020

Reduction of BM 15.766-induced 7-dehydrocholesterol accumulation by bezafibrate and mevinolin in rats. A non-isotopic in vivo test system for compounds reducing cholesterol synthesis

1 reference

12 December 2020

Terbinafine: mode of action and properties of the squalene epoxidase inhibition

1 reference

12 December 2020

Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth

1 reference

12 December 2020

Effects of BM 15.766 on serum lipids in rats

1 reference

12 December 2020

The effect of compactin, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase activity, on cholesterogenesis and serum cholesterol levels in rats and chicks

1 reference

12 December 2020

RG 12561 (dalvastatin): a novel synthetic inhibitor of HMG-CoA reductase and cholesterol-lowering agent

1 reference

12 December 2020

NB-598: a potent competitive inhibitor of squalene epoxidase

1 reference

12 December 2020

Non-sterol compounds that regulate cholesterogenesis. Analogues of farnesyl pyrophosphate reduce 3-hydroxy-3-methylglutaryl-coenzyme A reductase levels.

1 reference

12 December 2020

Effects of specific inhibition of sterol biosynthesis on the uptake and utilization of low density lipoprotein cholesterol by HepG2 cells

1 reference

12 December 2020

Regulation of hepatic receptor-dependent degradation of LDL by mevinolin in rabbits with hypercholesterolemia induced by a wheat starch-casein diet

1 reference

12 December 2020

Cataracts produced by triparanol. (MER-29).

1 reference

12 December 2020

Squalestatin 1, a potent inhibitor of squalene synthase, which lowers serum cholesterol in vivo

1 reference

12 December 2020

Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase

1 reference

12 December 2020

Efficacy and long-term adverse effect pattern of lovastatin

1 reference

12 December 2020

CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species

1 reference

12 December 2020

Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00168762

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8717165%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

1 reference