(Q71331742)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8733945%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

title

A pharmacokinetic-pharmacodynamic model of tolerance to morphine analgesia during infusion in rats (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8733945%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

1 reference

D M Ouellet

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8733945%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

G M Pollack

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8733945%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

publication date

1 December 1995

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8733945%20AND%20SRC:MED&resulttype=core&format=json

Journal of Pharmacokinetics and Pharmacodynamics

17 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8733945%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

volume

23

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8733945%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

page(s)

531-549

1 reference

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17 October 2019

issue

6

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https://scigraph.springernature.com/pub.10.1007/bf02353460

17 October 2019

exact match

0 references

cites work

Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model

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12 December 2020

Morphine-3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat

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12 December 2020

A MOLECULAR BASIS FOR DRUG ACTION.

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12 December 2020

Affinity and intrinsic-activity in the theory of competitive- and non-competitive inhibition and an analysis of some forms of dualism in action

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High-dose morphine and methadone in cancer patients. Clinical pharmacokinetic considerations of oral treatment

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12 December 2020

Time course characteristics of tolerance development to continuously infused antinociceptive agents in rat spinal cord

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12 December 2020

Biochemical basis for analgesic activity of morphine-6-glucuronide. I. Penetration of morphine-6-glucuronide in the brain of rats.

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12 December 2020

Mechanisms of cellular adaptive sensitivity changes: applications to opioid tolerance and dependence

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12 December 2020

Fast reliable assay for morphine and its metabolites using high-performance liquid chromatography and native fluorescence detection

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12 December 2020

Benefit from and tolerance to continuous intrathecal infusion of morphine for intractable cancer pain

1 reference

12 December 2020

A selective kappa-opioid agonist, U-50,488H, blocks the development of tolerance to morphine analgesia in rats

1 reference

12 December 2020

Kinetics of cocaine distribution, elimination, and chronotropic effects.

1 reference

12 December 2020

Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.

1 reference

12 December 2020

The treatment of cancer pain

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12 December 2020

Pharmacodynamic model of tolerance: application to nicotine

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12 December 2020

Modeling of tolerance development and rebound effect during different intravenous administrations of morphine to rats

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12 December 2020

Acute tolerance in morphine analgesia: continuous infusion and single injection in rats

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12 December 2020

Analgesic activity of morphine-6-glucuronide

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12 December 2020

Neurobiological mechanisms of opioid tolerance and dependence

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12 December 2020

Non-competitive nature of the antagonistic mechanism responsible for tolerance development to opiate-induced analgesia

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Tolerance to alprazolam after intravenous bolus and continuous infusion: psychomotor and EEG effects.

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Morphine kinetics in cancer patients

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12 December 2020

Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine

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12 December 2020

Morphine-3-glucuronide--a potent antagonist of morphine analgesia

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12 December 2020

Acute tolerance to furosemide diuresis in humans. Pharmacokinetic-pharmacodynamic modeling.

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12 December 2020

I.v. infusion of opioids for cancer pain: clinical review and guidelines for use.

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12 December 2020

Morphine metabolism in cancer patients on increasing oral doses--no evidence for autoinduction or dose-dependence

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12 December 2020

Receptor alterations and drug tolerance

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12 December 2020

Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

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12 December 2020

A pharmacodynamic model to predict the time dependent adaptation of dopaminergic activity during constant concentrations of haloperidol

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12 December 2020

Differential inhibition of hepatic morphine UDP-glucuronosyltransferases by metal ions

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12 December 2020

Morphine-6-glucuronide, a potent mu agonist.

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12 December 2020

Pharmacokinetic-pharmacodynamic modeling of caffeine: tolerance to pressor effects

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12 December 2020

Rapid, high-sensitivity method for measurement of morphine in guinea-pig serum

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12 December 2020

Comparison of intermittent bolus with continuous infusion of epidural morphine in the treatment of severe cancer pain

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12 December 2020

A MOLECULAR BASIS FOR DRUG ACTION. THE INTERACTION OF ONE OR MORE DRUGS WITH DIFFERENT RECEPTORS.

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12 December 2020

Kinetics of pharmacologic response

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12 December 2020

Analgesia and tolerance to intrathecal morphine and norepinephrine infusion via implanted mini-osmotic pumps in the rat

1 reference

12 December 2020

Species differences in metabolism of codeine: urinary excretion of codeine glucuronide, morphine-3-glucuronide and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits

1 reference

12 December 2020

Disposition of morphine in rat brain: relationship to biological activity.

1 reference

12 December 2020

Induction of tolerance and withdrawal in rats receiving morphine in the spinal subarachnoid space

1 reference

12 December 2020

Species difference of site-selective glucuronidation of morphine

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of morphine-3-glucuronide in rats and its influence on the antinociceptive effect of morphine

1 reference

12 December 2020

A review of the role of anti-opioid peptides in morphine tolerance and dependence

1 reference

12 December 2020

The impact of pain on the patient with cancer

1 reference

12 December 2020

Pharmacokinetics of morphine in striatum and nucleus accumbens: relationship to pharmacological actions.

1 reference

12 December 2020

Relation between morphine pharmacokinetics and analgesia

1 reference

12 December 2020

Quantification of effect delay and acute tolerance development to morphine in the rat

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02353460

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8733945%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

1 reference