(Q71377766)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8750925%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

title

Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans (English)

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18 October 2019

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3

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18 October 2019

author name string

D Busse

1

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18 October 2019

J Cosme

2

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18 October 2019

H K Kroemer

4

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18 October 2019

M Eichelbaum

5

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18 October 2019

publication date

1 December 1995

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Naunyn-Schmiedeberg's Archives of Pharmacology

18 October 2019

published in

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18 October 2019

volume

353

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18 October 2019

issue

1

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18 October 2019

page(s)

116-121

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Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

18 October 2019

cites work

1 reference

12 December 2020

Polymorphism in hydroxylation of mephenytoin and hexobarbital stereoisomers in relation to hepatic P-450 human-2

1 reference

12 December 2020

Biochemistry and molecular biology of the human CYP2C subfamily

1 reference

12 December 2020

Near-total reduction in verapamil bioavailability by rifampin. Electrocardiographic correlates

1 reference

12 December 2020

Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9

1 reference

12 December 2020

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

1 reference

12 December 2020

In vitro oxidation of oxicam NSAIDS by a human liver cytochrome P450

1 reference

12 December 2020

Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9

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12 December 2020

Verapamil and drug metabolism by the cytochrome P450 isoform CYP1A2

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12 December 2020

Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans

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12 December 2020

Substrate-selective inhibition by verapamil and diltiazem: differential disposition of antipyrine and theophylline in humans

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12 December 2020

Cytochrome P450TB (CYP2C): a major monooxygenase catalyzing diclofenac 4'-hydroxylation in human liver

1 reference

12 December 2020

Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes

1 reference

12 December 2020

Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites

1 reference

12 December 2020

Oxidative metabolism of hexobarbital in human liver: relationship to polymorphic S-mephenytoin 4-hydroxylation

1 reference

12 December 2020

Interaction of verapamil and cimetidine: stereochemical aspects of drug metabolism, drug disposition and drug action

1 reference

12 December 2020

Predictability of the in vivo metabolism of verapamil from in vitro data: contribution of individual metabolic pathways and stereoselective aspects

1 reference

12 December 2020

Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae

1 reference

12 December 2020

Effects of chronic phenobarbital on verapamil disposition in humans

1 reference

12 December 2020

Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily

1 reference

12 December 2020

The metabolism of DL-[14C]verapamil in man

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12 December 2020

Verapamil inhibits cyclosporin metabolism

1 reference

12 December 2020

Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

1 reference

12 December 2020

Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

1 reference

12 December 2020

Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8

1 reference

12 December 2020

Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug

1 reference

12 December 2020

Identification of P450 enzymes involved in metabolism of verapamil in humans

1 reference

12 December 2020

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

1 reference

12 December 2020

Specificity of in vitro covalent binding of tienilic acid metabolites to human liver microsomes in relationship to the type of hepatotoxicity: comparison with two directly hepatotoxic drugs.

1 reference

12 December 2020

Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

1 reference

12 December 2020

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

1 reference

12 December 2020

Protein measurement with the Folin phenol reagent

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12 December 2020

Cytochrome P-450 human-2 (P-450IIC9) in mephenytoin hydroxylation polymorphism in human livers: differences in substrate and stereoselectivities among microheterogeneous P-450IIC species expressed in yeasts

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12 December 2020

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

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12 December 2020

Genetic polymorphism of human cytochrome P-450 (S)-mephenytoin 4-hydroxylase. Studies with human autoantibodies suggest a functionally altered cytochrome P-450 isozyme as cause of the genetic deficiency

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00168924

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8750925%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

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