(Q71611362)

English

Biotransformation of the antiemetic 5-HT3 antagonist tropisetron in liver and kidney slices of human, rat and dog with a comparison to in vivo

scientific article published on 01 January 1996

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8839677%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

Biotransformation of the antiemetic 5-HT3 antagonist tropisetron in liver and kidney slices of human, rat and dog with a comparison to in vivo (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8839677%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

author name string

A E Vickers

1

1 reference

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19 October 2019

V Fischer

2

1 reference

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19 October 2019

M S Connors

3

1 reference

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19 October 2019

W A Biggi

4

1 reference

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19 October 2019

F Heitz

5

1 reference

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19 October 2019

J P Baldeck

6

1 reference

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19 October 2019

K Brendel

7

1 reference

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19 October 2019

publication date

1 January 1996

1 reference

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19 October 2019

European Journal of Drug Metabolism and Pharmacokinetics

1 reference

Europe PubMed Central

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19 October 2019

21

1 reference

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19 October 2019

43-50

1 reference

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19 October 2019

1

1 reference

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19 October 2019

https://scigraph.springernature.com/pub.10.1007/bf03190277

0 references

Extrapyramidal reactions with high-dose metoclopramide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive interaction of agonists and antagonists with 5-HT3 recognition sites in membranes of neuroblastoma cells labelled with [3H]ICS 205-930.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tropisetron. A review of the clinical experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of chemotherapy-induced nausea and emesis in patients responding poorly to previous antiemetic therapy. Comparing tropisetron with optimised standard antiemetic therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maintenance of adult rat liver slices in dynamic organ culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The depolarizing action of 5-hydroxytryptamine on rabbit vagal afferent and sympathetic neurones in vitro and its selective blockade by ICS 205-930.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The polymorphic cytochrome P-4502D6 is involved in the metabolism of both 5-hydroxytryptamine antagonists, tropisetron and ondansetron

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro characterization of cytochrome P450 catalysed metabolism of the antiemetic tropisetron

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the tropine indole-3-carboxylate ICS 205-930 by differentiated rat and human hepatoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological and anti-emetic properties of ondansetron.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunochemical comparison and quantitation of microsomal flavin-containing monooxygenases in various hog, mouse, rat, rabbit, dog, and human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that 5-hydroxytryptamine3 receptors mediate cytotoxic drug and radiation-evoked emesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tropisetron plus haloperidol to ameliorate nausea and vomiting associated with high-dose alkylating agent cancer chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cocaine hepatotoxicity in cultured liver slices: a species comparison.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and metabolism of the 5-hydroxytryptamine antagonist tropisetron after single oral doses in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/8839677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF03190277

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8839677%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8839677%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

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