(Q71843540)

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Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments

scientific article published on 01 January 1995

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7600303%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments (English)

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7600303%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

B-lymphocyte differentiation antigens

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7600303

6 June 2024

antigen presentation

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6 June 2024

author name string

F. Castellino

1

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6 June 2024

R. N. Germain

2

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6 June 2024

language of work or name

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National Center for Biotechnology Information

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6 June 2024

publication date

1 January 1995

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21 October 2019

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https://doi.org/10.1016/1074-7613(95)90080-2

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6 June 2024

https://api.elsevier.com/content/article/PII:1074761395900802?httpAccept=text/xml

1 reference

10.1016/1074-7613(95)90080-2

https://api.crossref.org/works/10.1016/1074-7613(95)90080-2

6 June 2024

https://api.elsevier.com/content/article/PII:1074761395900802?httpAccept=text/plain

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10.1016/1074-7613(95)90080-2

https://api.crossref.org/works/10.1016/1074-7613(95)90080-2

6 June 2024

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Europe PubMed Central

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21 October 2019

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Europe PubMed Central

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21 October 2019

1

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Europe PubMed Central

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21 October 2019

73-88

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7600303%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

1 reference

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Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes

1

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Role for intracellular proteases in the processing and transport of class II HLA antigens

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Identification of two lysosomal membrane glycoproteins

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Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

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Transport and expression of HLA class-II glycoproteins

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Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes

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The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules

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HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

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MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation

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MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

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The biochemistry and cell biology of antigen processing and presentation

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Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules

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Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins

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Regulation of intracellular membrane transport.

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Membrane traffic in endocytosis: insights from cell-free assays

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Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment

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Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells

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Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane

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Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

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Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors

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Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virus

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Irreversible association of peptides with class II MHC molecules in living cells.

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Intracellular transport of class II MHC molecules directed by invariant chain.

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Antigen presentation enhanced by the alternatively spliced invariant chain gene product p41.

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Separation of subcellular compartments containing distinct functional forms of MHC class II

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Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.

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A role for peptide in determining MHC class II structure

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Making class II presentable

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Intracellular distribution of the MHC class II molecules and the associated invariant chain (Ii) in different cell lines

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Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways

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Identifiers

10.1016/1074-7613(95)90080-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7600303%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7600303%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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