(Q71879250)

English

Binding Sites for Neurotoxins and Cholinergic Ligands in Peripheral and Neuronal Nicotinic Receptors Studies with Synthetic Receptor Sequencesa

scientific article published on May 10, 1995

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7611670%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

Binding sites for neurotoxins and cholinergic ligands in peripheral and neuronal nicotinic receptors. Studies with synthetic receptor sequences (English)

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21 October 2019

Binding Sites for Neurotoxins and Cholinergic Ligands in Peripheral and Neuronal Nicotinic Receptors Studies with Synthetic Receptor Sequencesa (English)

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10.1111/J.1749-6632.1995.TB17470.X

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18 June 2024

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B. M. Conti-Fine

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18 June 2024

A. Maelicke

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18 June 2024

S. Reinhardt-Maelicke

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18 June 2024

V. Chiappinelli

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18 June 2024

K. E. McLane

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1 May 1995

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21 October 2019

10 May 1995

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National Center for Biotechnology Information

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18 June 2024

full work available at URL

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1749-6632.1995.tb17470.x

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10.1111/J.1749-6632.1995.TB17470.X

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18 June 2024

https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1749-6632.1995.tb17470.x

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10.1111/J.1749-6632.1995.TB17470.X

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18 June 2024

Annals of the New York Academy of Sciences

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21 October 2019

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21 October 2019

133-152

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21 October 2019

The nicotinic acetylcholine receptor: structure and autoimmune pathology

1

1 reference

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Expression of functional acetylcholine receptor from cloned cDNAs

2

1 reference

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Restoration of 125I-alpha-bungarotoxin binding activity to the alpha subunit of Torpedo acetylcholine receptor isolated by gel electrophoresis in sodium dodecyl sulfate.

3

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High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate.

4

1 reference

10.1111/J.1749-6632.1995.TB17470.X

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Binding of alpha-bungarotoxin to isolated alpha subunit of the acetylcholine receptor of Torpedo californica: quantitative analysis with protein blots

5

1 reference

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Protein kinase C contains a pseudosubstrate prototope in its regulatory domain

6

1 reference

10.1111/J.1749-6632.1995.TB17470.X

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18 June 2024

Molecular Pharmacology

7

34

643

author name string

Wilson P. T.

publication date

1988

1 reference

10.1111/J.1749-6632.1995.TB17470.X

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18 June 2024

Mapping of a cholinergic binding site by means of synthetic peptides, monoclonal antibodies, and alpha-bungarotoxin

8

1 reference

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18 June 2024

Alpha-bungarotoxin and the competing antibody WF6 interact with different amino acids within the same cholinergic subsite

11

1 reference

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Amino acid residues forming the interface of a neuronal nicotinic acetylcholine receptor with kappa-bungarotoxin: a study using single residue substituted peptide analogs

12

1 reference

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Structural determinants of alpha-bungarotoxin binding to the sequence segment 181-200 of the muscle nicotinic acetylcholine receptor alpha subunit: effects of cysteine/cystine modification and species-specific amino acid substitutions

13

1 reference

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Structural determinants within residues 180-199 of the rodent alpha 5 nicotinic acetylcholine receptor subunit involved in alpha-bungarotoxin binding

15

1 reference

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Solution conformation of a deoxynucleotide containing tandem G.A mismatched base pairs and 3'-overhanging ends in d(GTGAACTT)2

16

1 reference

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Amino acid residues within the sequence region alpha 55-74 of Torpedo nicotinic acetylcholine receptor interacting with antibodies to the main immunogenic region and with snake alpha-neurotoxins

17

1 reference

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An alpha-bungarotoxin-binding sequence on the Torpedo nicotinic acetylcholine receptor alpha-subunit: conservative amino acid substitutions reveal side-chain specific interactions

18

1 reference

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Coexpression of two distinct muscle acetylcholine receptor alpha-subunits during development.

20

1 reference

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The human muscle nicotinic acetylcholine receptor alpha-subunit exist as two isoforms: a novel exon

21

1 reference

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Coordinate regulation of RNAs encoding two isoforms of the rat muscle nicotinic acetylcholine receptor beta-subunit

22

1 reference

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Primary structure and expression of beta 2: a novel subunit of neuronal nicotinic acetylcholine receptors

24

1 reference

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Neurotoxins distinguish between different neuronal nicotinic acetylcholine receptor subunit combinations

25

1 reference

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The functional diversity of the neuronal nicotinic acetylcholine receptors is increased by a novel subunit: beta 4.

27

1 reference

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Functional expression of a new pharmacological subtype of brain nicotinic acetylcholine receptor

28

1 reference

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Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes.

29

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Peptide toxins from venomous Conus snails

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18 June 2024

Monoclonal antibodies against synthetic sequences of the nicotinic receptor cross-react fully with the native receptor and reveal the transmembrane disposition of their epitopes

32

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10.1111/J.1749-6632.1995.TB17470.X

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The amino terminal half of the nicotinic beta-subunit extracellular domain regulates the kinetics of inhibition by neuronal bungarotoxin

33

1 reference

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Functional contribution of neuronal AChR subunits revealed by antisense oligonucleotides.

34

1 reference

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The alpha 5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain

35

1 reference

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Main Immunogenic Region of Torpedo Electroplax and Human Muscle Acetylcholine Receptor: Localization and Microheterogeneity Revealed by the Use of Synthetic Peptides

37

1 reference

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Mutations affecting agonist sensitivity of the nicotinic acetylcholine receptor

38

1 reference

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Organization of ligand binding sites at the acetylcholine receptor: a study with monoclonal antibodies

40

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Structure and activity of acetylcholine

42

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The binding site for alpha-bungarotoxin resides in the sequence 188-201 of the alpha-subunit of acetylcholine receptor: structure, conformation and binding characteristics of peptide [Lys] 188-201

43

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10.1111/J.1749-6632.1995.TB17470.X

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Molecular Pharmacology

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657

author name string

Luetje C. W.

publication date

1992

1 reference

10.1111/J.1749-6632.1995.TB17470.X

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18 June 2024

Brain and muscle nicotinic acetylcholine receptors are different but homologous proteins

46

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Neuronal-type alpha-bungarotoxin receptors and the alpha 5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines

48

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Molecular evolution of the binding site of the acetylcholine receptor

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Neutralization of Viperidae and Elapidae snake venoms by sera of different animals

51

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Substitution of Torpedo acetylcholine receptor .alpha.1-subunit residues with snake .alpha.1- and rat nerve .alpha.3-subunit residues in recombinant fusion proteins: effect on .alpha.-bungarotoxin binding

52

1 reference

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Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence.

54

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Muscarinic receptor subtypes

55

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Peptide sequences that target cytosolic proteins for lysosomal proteolysis

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10.1111/J.1749-6632.1995.TB17470.X

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18 June 2024

Mutations affecting agonist sensitivity of the nicotinic acetylcholine receptor

57

1 reference

10.1111/J.1749-6632.1995.TB17470.X

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18 June 2024

The crystal structure of alpha-bungarotoxin at 2.5 A resolution: relation to solution structure and binding to acetylcholine receptor

58

1 reference

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Structural studies of .alpha.-bungarotoxin. 2. Proton NMR assignments via an improved relayed coherence transfer nuclear Overhauser enhancement experiment

59

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10.1111/J.1749-6632.1995.TB17470.X

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Structural studies of .alpha.-bungarotoxin. 1. Sequence-specific proton NMR resonance assignments

60

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Occurrence and role of cis peptide bonds in protein structures

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Effects of mutations of Torpedo acetylcholine receptor alpha 1 subunit residues 184-200 on alpha-bungarotoxin binding in a recombinant fusion protein

63

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Analysis and prediction of the different types of beta-turn in proteins

64

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10.1111/J.1749-6632.1995.TB17470.X

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Comparison of the toxin binding sites of the nicotinic acetylcholine receptor from Drosophila to human.

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Journal of Biological Chemistry

67

266

23364

author name string

Cohen J. B.

publication date

1991

1 reference

10.1111/J.1749-6632.1995.TB17470.X

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18 June 2024

Acetylcholine binding by a synthetic receptor: implications for biological recognition

68

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Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein

69

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Amino acid sequence of .kappa.-flavitoxin: establishment of a new family of snake venom neurotoxins

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A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

71

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Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain

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18 June 2024

Identifiers

10.1111/J.1749-6632.1995.TB17470.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7611670%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7611670%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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