(Q72078645)

English

Cryopreservation and long-term storage of primary rat hepatocytes: effects on substrate-specific cytochrome P450-dependent activities and unscheduled DNA synthesis

scientific article published on 01 October 1993

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

Cryopreservation and long-term storage of primary rat hepatocytes: effects on substrate-specific cytochrome P450-dependent activities and unscheduled DNA synthesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

author name string

J G Shaddock

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

J E Snawder

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

D A Casciano

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

publication date

1 October 1993

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

Cell Biology and Toxicology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

4

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

345-357

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

Sex change in cytochrome P-450 phenotype by growth hormone treatment of adult rat hepatocytes maintained in a culture system on matrigel

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of sister-chromatid exchanges by direct and indirect mutagens in human lymphocytes, co-cultured with intact rat liver cells. Effect of enzyme induction and preservation of the liver cells by freezing in liquid nitrogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unscheduled DNA synthesis tests. A report of the U.S. Environmental Protection Agency Gene-Tox Program

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promutagen activation by freshly isolated and cryopreserved rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statistical criteria for evaluating chemicals as positive or negative in the hepatocyte/DNA repair assay.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of the potential genotoxicity of methapyrilene and related antihistamines using the hepatocyte/DNA repair assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential stabilization of cytochrome P-450 isoenzymes in primary cultures of adult rat liver parenchymal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of cryopreserved hepatocytes for unscheduled DNA synthesis assays.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimization of cryopreservation procedures for rat and human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cryopreservation of isolated rat hepatocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450IIE1: roles in nitrosamine metabolism and mechanisms of regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P-450 activity in hepatocytes following cryopreservation and monolayer culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cryopreservation of rat and dog hepatocytes for studies of xenobiotic metabolism and activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The induction and competitive inhibition of a high affinity microsomal nitrosodimethylamine demethylase by ethanol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical functionality and recovery of hepatocytes after deep freezing storage

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further improvements in the hepatocyte primary culture DNA repair test for carcinogens: detection of carcinogenic biphenyl derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of microsomal cytochrome P-450s

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preservation of freshly isolated liver cells in liquid nitrogen at − 196°C

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pretreatment with mixed-function oxidase inducers increases the sensitivity of the hepatocyte/DNA repair assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reliability of the hepatocyte primary culture/DNA repair test in testing of coded carcinogens and noncarcinogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of chemical carcinogens by unscheduled DNA synthesis in rat liver primary cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of pretreatment with hepatic mixed-function oxidase inducers on the genotoxicity of four rat carcinogens in the hepatocyte/DNA repair assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged maintenance of active cytochrome P-450 in adult rat hepatocytes co-cultured with another liver cell type

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential stability of drug-metabolizing enzyme activities in primary rat hepatocytes, cultured in the absence or presence of dexamethasone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of genotoxic and epigenetic carcinogens in liver culture systems.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long term maintenance and induction of cytochrome P-450 in rat liver cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00754463

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039011%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

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