(Q72272350)

English

Overproduction of the acyl carrier protein component of a type II polyketide synthase stimulates production of tetracenomycin biosynthetic intermediates in Streptomyces glaucescens

scientific article published on 01 January 1994

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8119862%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

Overproduction of the acyl carrier protein component of a type II polyketide synthase stimulates production of tetracenomycin biosynthetic intermediates in Streptomyces glaucescens (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8119862%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

Streptomyces glaucescens

1 reference

2-Naphthacenecarboxylic acid, 6,6a,7,10,10a,11-hexahydro-6a,7,10a,12-tetrahydroxy-3,8-dimethoxy-1-methyl-6,10,11-trioxo-, methyl ester

1 reference

author name string

H Decker

1

1 reference

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25 October 2019

R G Summers

2

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8119862%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

C R Hutchinson

3

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25 October 2019

publication date

1 January 1994

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25 October 2019

full work available at URL

https://www.jstage.jst.go.jp/article/antibiotics1968/47/1/47_1_54/_pdf

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19 March 2024

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The Journal of Antibiotics

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Europe PubMed Central

PubMed publication ID

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25 October 2019

47

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25 October 2019

1

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25 October 2019

54-63

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25 October 2019

online access status

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access restriction status

1 reference

based on heuristic

inferred from online access status

Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22.

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/J.1460-2075.1989.TB08413.X

Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis.

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/J.1460-2075.1989.TB08414.X

Cloning and heterologous expression of a gene cluster for the biosynthesis of tetracenomycin C, the anthracycline antitumor antibiotic of Streptomyces glaucescens

1 reference

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Isolation of tetracenomycin C-nonproducing Streptomyces glaucescens mutants

1 reference

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Expression of holo and apo forms of spinach acyl carrier protein-I in leaves of transgenic tobacco plants

1 reference

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Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins

1 reference

12 April 2024

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Modular organization of genes required for complex polyketide biosynthesis

1 reference

12 April 2024

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Metabolic products of microorganisms. 249. Tetracenomycins B3 and D3, key intermediates of the elloramycin and tetracenomycin C biosynthesis

2 references

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12 April 2024

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Genetic engineering of beta-lactam antibiotic biosynthetic pathways in filamentous fungi

1 reference

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An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea

1 reference

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Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius

1 reference

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Construction of a 7-aminocephalosporanic acid (7ACA) biosynthetic operon and direct production of 7ACA in Acremonium chrysogenum

1 reference

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Construction of metabolic operons catalyzing the de novo biosynthesis of indigo in Escherichia coli.

1 reference

12 April 2024

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Metabolic products of microorganisms. 175. Tetracenomycin C (author's transl)

1 reference

12 April 2024

https://opencitations.net/index/api/v1/references/10.7164/ANTIBIOTICS.47.54

Overproduction and localization of components of the polyketide synthase of Streptomyces glaucescens involved in the production of the antibiotic tetracenomycin C

2 references

12 April 2024

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.173.20.6475-6483.1991

Anthracycline metabolites of tetracenomycin C-nonproducing Streptomyces glaucescens mutants

1 reference

12 April 2024

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Transcriptional analysis of the Streptomyces glaucescens tetracenomycin C biosynthesis gene cluster

1 reference

12 April 2024

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Production of a hybrid macrolide antibiotic in Streptomyces ambofaciens and Streptomyces lividans by introduction of a cloned carbomycin biosynthetic gene from Streptomyces thermotolerans

1 reference

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Plasmid effects on secondary metabolite production by a streptomycete synthesizing an anthelmintic macrolide

1 reference

12 April 2024

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The improving prospects for yield increase by genetic engineering in antibiotic-producing Streptomycetes

1 reference

12 April 2024

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Nucleotide sequences and heterologous expression of tcmG and tcmP, biosynthetic genes for tetracenomycin C in Streptomyces glaucescens

1 reference

12 April 2024

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A macrolide 3-O-acyltransferase gene from the midecamycin-producing species Streptomyces mycarofaciens

2 references

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.174.15.5141-5144.1992

Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclase-dehydratase-O-methyl transferase

2 references

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https://opencitations.net/index/api/v1/citations/10.1128/JB.174.6.1810-1820.1992

Purification and characterization of the acyl carrier protein of the Streptomyces glaucescens tetracenomycin C polyketide synthase

1 reference

12 April 2024

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Production of ‘hybrid’ antibiotics by genetic engineering

1 reference

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Production of 2-Keto-L-Gulonate, an Intermediate in L-Ascorbate Synthesis, by a Genetically Modified Erwinia herbicola

1 reference

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Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator.

1 reference

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The tcmVI region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens encodes the tetracenomycin F1 monooxygenase, tetracenomycin F2 cyclase, and, most likely, a second cyclase

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https://opencitations.net/index/api/v1/citations/10.1128/JB.175.23.7571-7580.1993

Sequence and transcriptional analysis of the Streptomyces glaucescens tcmAR tetracenomycin C resistance and repressor gene loci

1 reference

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Cloning and expression of the tyrosinase gene from Streptomyces antibioticus in Streptomyces lividans

1 reference

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Identifiers

10.7164/ANTIBIOTICS.47.54

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8119862%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8119862%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

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