(Q72897734)

English

Effect of quinidine on the interconversion kinetics between haloperidol and reduced haloperidol in humans: implications for the involvement of cytochrome P450IID6

scientific article published on 01 January 1993

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scholarly article

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30 October 2019

Effect of quinidine on the interconversion kinetics between haloperidol and reduced haloperidol in humans: implications for the involvement of cytochrome P450IID6 (English)

1 reference

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30 October 2019

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author name string

D Young

1

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30 October 2019

K K Midha

2

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30 October 2019

M J Fossler

3

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30 October 2019

E M Hawes

4

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30 October 2019

J W Hubbard

5

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30 October 2019

G McKay

6

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30 October 2019

E D Korchinski

7

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30 October 2019

publication date

1 January 1993

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30 October 2019

European Journal of Clinical Pharmacology

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30 October 2019

44

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30 October 2019

433-438

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30 October 2019

5

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30 October 2019

https://scigraph.springernature.com/pub.10.1007/bf00315539

0 references

Intersubject variation in the pharmacokinetics of haloperidol and reduced haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of reduced haloperidol to haloperidol: involvement of human P450IID6 (sparteine/debrisoquine monooxygenase).

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinidine but not quinine inhibits in man the oxidative metabolic routes of methoxyphenamine which involve debrisoquine 4-hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HALOPERIDOL METABOLISM AND ANTIPSYCHOTIC EFFECT IN SCHIZOPHRENIA

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of antisera in the isolation of human specific conjugates of haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversions between haloperidol and reduced haloperidol in schizophrenic patients and guinea pigs: a steady-state study

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol and reduced haloperidol plasma levels in selected schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and Identification of a Metabolite of Haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions in the renal and biliary elimination of digoxin: stereoselective difference between quinine and quinidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol reduction can be assayed in human red blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced haloperidol: Effects on striatal dopamine metabolism and conversion to haloperidol in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of quinidine on plasma concentrations of digoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinidine-digoxin interaction: Pharmacokinetics, underlying mechanism and clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol reductase in human and guinea pig livers

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol disposition is dependent on the debrisoquine hydroxylation phenotype: increased plasma levels of the reduced metabolite in poor metabolizers

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Debrisoquine oxidation phenotype during neuroleptic monotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversion between haloperidol and reduced haloperidol in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinidine and the identification of drugs whose elimination is impaired in subjects classified as poor metabolizers of debrisoquine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The determination of essential clearance, volume, and residence time parameters of recirculating metabolic systems: the reversible metabolism of methylprednisolone and methylprednisone in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversion between haloperidol and reduced haloperidol in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An ultrasensitive method for the measurement of haloperidol and reduced haloperidol in plasma by high-performance liquid chromatography with coulometric detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/8359179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00315539

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8359179%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8359179%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

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