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English
Rational engineering of activity and specificity in a serine protease
scientific article published on 01 February 1997
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scholarly article
1 reference
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Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
title
Rational engineering of activity and specificity in a serine protease
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
author name string
Dang QD
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
Guinto ER
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
di Cera E
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
publication date
1 February 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
published in
Nature Biotechnology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
volume
15
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
page(s)
146-149
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/nbt0297-146
0 references
cites work
Conservation and variability in the structures of serine proteinases of the chymotrypsin family
1 reference
stated in
Crossref
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retrieved
7 January 2021
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Evolution of Proteolytic Enzymes
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
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7 January 2021
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The coagulation cascade: initiation, maintenance, and regulation
1 reference
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Crossref
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7 January 2021
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Complement system proteins which interact with C3b or C4b A superfamily of structurally related proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
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The role of easter, an apparent serine protease, in organizing the dorsal-ventral pattern of the Drosophila embryo.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
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Ventralizing signal determined by protease activation in Drosophila embryogenesis.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
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7 January 2021
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inferred from DOI database lookup
Reconstructing the evolution of vertebrate blood coagulation from a consideration of the amino acid sequences of clotting proteins
1 reference
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Crossref
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7 January 2021
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Evolutionary families of peptidases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
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7 January 2021
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Structural basis of substrate specificity in the serine proteases
1 reference
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Crossref
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retrieved
7 January 2021
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Redesigning trypsin: alteration of substrate specificity
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
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Converting trypsin to chymotrypsin: the role of surface loops
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
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inferred from DOI database lookup
Residue 225 determines the Na(+)-induced allosteric regulation of catalytic activity in serine proteases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An allosteric switch controls the procoagulant and anticoagulant activities of thrombin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
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Thrombin is a Na(+)-activated enzyme
1 reference
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Crossref
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7 January 2021
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Large heat capacity change in a protein-monovalent cation interaction
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
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7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced protein C activation and inhibition of fibrinogen cleavage by a thrombin modulator
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Na+ binding site of thrombin
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
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The molecular environment of the Na+ binding site of thrombin
1 reference
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Crossref
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7 January 2021
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Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp
1 reference
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Crossref
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7 January 2021
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The interaction of thrombin with fibrinogen. A structural basis for its specificity
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
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7 January 2021
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Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conversion of thrombin into an anticoagulant by protein engineering
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
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7 January 2021
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Prothrombin Salakta: substitution of glutamic acid-466 by alanine reduces the fibrinogen clotting activity and the esterase activity
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
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7 January 2021
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Glu-192----Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Single amino acid substitutions dissociate fibrinogen-clotting and thrombomodulin-binding activities of human thrombin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dominant and recessive alleles of the Drosophila easter gene are point mutations at conserved sites in the serine protease catalytic domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of residues linked to the slow-->fast transition of thrombin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preparation of bovine prethrombin 2: use of Acutin and activation with prothrombinase or Ecarin
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Release of fibrinopeptides by the slow and fast forms of thrombin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
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7 January 2021
based on heuristic
inferred from DOI database lookup
Quantifying thrombin-catalyzed release of fibrinopeptides from fibrinogen using high-performance liquid chromatography.
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Theory of allosteric effects in serine proteases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT0297-146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NBT0297-146
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PubMed publication ID
9035139
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9035139
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9035139%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
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