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English
Site-directed mutagenesis of squalene-hopene cyclase: altered substrate specificity and product distribution
scientific article published on 01 August 2000
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
title
Site-directed mutagenesis of squalene-hopene cyclase: altered substrate specificity and product distribution
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
main subject
squalene
1 reference
based on heuristic
inferred from title
author name string
T Dang
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
G D Prestwich
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
publication date
1 August 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
published in
Chemistry and Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
volume
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
issue
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
page(s)
643-649
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
cites work
Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Stereochemistry of Polyene Cyclization
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
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Managing and manipulating carbocations in biology: terpenoid cyclase structure and mechanism
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https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
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Isoprenoid biosynthesis: manifold chemistry catalyzed by similar enzymes
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7 January 2021
based on heuristic
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Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
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Structure and function of a squalene cyclase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Site-directed mutagenesis of putative active-site residues in squalene-hopene cyclase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Squalene-hopene cyclase from Bradyrhizobium japonicum: cloning, expression, sequence analysis and comparison to other triterpenoid cyclases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Photoaffinity labeling of oxidosqualene cyclase and squalene cyclase by a benzophenone-containing inhibitor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The binding site for an inhibitor of squalene:hopene cyclase determined using photoaffinity labeling and molecular modeling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on the Substrate Binding Segments and Catalytic Action of Lanosterol Synthase. Affinity Labeling with Carbocations Derived from Mechanism-Based Analogs of 2,3-Oxidosqualene and Site-Directed Mutagenesis Probes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A lupane triterpenoid from Maerua oblongifolia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
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Achilleol A: A new monocyclic triterpene skeleton from Achillea odorata L.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
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Camelliols A-C, three novel incompletely cyclized triterpene alcohols from sasanqua oil (Camellia sasanqua)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Properties of purified squalene-hopene cyclase from Bacillus acidocaldarius
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Methodology for the Preparation of Pure RecombinantS. cerevisiaeLanosterol Synthase Using a Baculovirus Expression System. Evidence That Oxirane Cleavage and A-Ring Formation Are Concerted in the Biosynthesis of Lanosterol from 2,3-Oxidosqualene
1 reference
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https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Steric bulk at position 454 in Saccharomyces cerevisiae lanosterol synthase influences B-ring formation but not deprotonation
1 reference
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https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of the DXDDTA motif in squalene-hopene cyclase by site-directed mutagenesis experiments: initiation site of the polycyclization reaction and stabilization site of the carbocation intermediate of the initially cyclized A-ring
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis of carotenoid cyclase inhibition
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Aging of di-isopropyl-phosphorylated human butyrylcholinesterase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning, expression, and sequencing of squalene-hopene cyclase, a key enzyme in triterpenoid metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Determination of Enzyme Dissociation Constants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic studies on the function of all the conserved tryptophans involved inside and outside the QW motifs of squalene-hopene cyclase: stabilizing effect of the protein structure against thermal denaturation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900003-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-5521(00)00003-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PubMed publication ID
11048954
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11048954
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11048954%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
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