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PYK2 is an adhesion kinase in macrophages, localized in podosomes and activated by beta(2)-integrin ligation
scientific article published on 01 November 2000
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1 reference
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Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
title
PYK2 is an adhesion kinase in macrophages, localized in podosomes and activated by beta(2)-integrin ligation
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
author name string
Duong LT
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
Rodan GA
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
publication date
1 November 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
published in
Cytoskeleton
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
volume
47
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
page(s)
174-188
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
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The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas
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Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton
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Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling
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PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase
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The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways
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The role of the macrophage in immune regulation
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Csk suppression of Src involves movement of Csk to sites of Src activity
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A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1.
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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions
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Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells
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A calcium-dependent tyrosine kinase splice variant in human monocytes. Activation by a two-stage process involving adherence and a subsequent intracellular signal
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Human blood monocytes, but not alveolar macrophages, reveal increased CD11b/CD18 expression and adhesion properties upon receptor-dependent activation
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Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins
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Rous sarcoma virus-transformed fibroblasts and cells of monocytic origin display a peculiar dot-like organization of cytoskeletal proteins involved in microfilament-membrane interactions
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Glycolipids of the mouse peritoneal macrophage. Alterations in amount and surface exposure of specific glycolipid species occur in response to inflammation and tumoricidal activation
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Activation of protein-tyrosine kinase Pyk2 is downstream of Syk in FcepsilonRI signaling
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Plasma fibronectin enhances phagocytosis of opsonized particles by human peripheral blood monocytes
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Tyrosine phosphorylation of the novel protein-tyrosine kinase RAFTK during an early phase of platelet activation by an integrin glycoprotein IIb-IIIa-independent mechanism.
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Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily
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Signaling through focal adhesion kinase
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The alphavbeta3 integrin regulates alpha5beta1-mediated cell migration toward fibronectin
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Different cell surface and phagocytic properties in mononuclear phagocytes from blood and alveoli. A comparative study of blood monocytes and alveolar macrophages from human nonsmokers using flow cytofluorometry
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Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm
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Activation of Pyk2 by stress signals and coupling with JNK signaling pathway
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21 January 2018
Lipopolysaccharide induces actin reorganization and tyrosine phosphorylation of Pyk2 and paxillin in monocytes and macrophages
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21 January 2018
Fibronectin and serum amyloid P component stimulate C3b- and C3bi-mediated phagocytosis in cultured human monocytes
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Identifiers
DOI
10.1002/1097-0169(200011)47:3<174::AID-CM2>3.0.CO;2-N
0 references
PubMed publication ID
11056520
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11056520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11056520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
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