(Q73143117)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Novel 5-cyclopropyl-1,4-benzodiazepin-2-ones as potent and selective I(Ks)-blocking class III antiarrhythmic agents (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

John W Butcher

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Nigel J Liverton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

David A Claremon

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Roger M Freidinger

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Nancy K Jurkiewicz

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Joseph J Lynch

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Joseph J Salata

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Jixin Wang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Christine M Dieckhaus

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Donald E Slaughter

10

1 reference

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1 November 2019

Kamlesh Vyas

11

1 reference

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1 November 2019

language of work or name

English

0 references

publication date

1 March 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

Bioorganic & Medicinal Chemistry Letters

1 November 2019

published in

1 reference

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1 November 2019

volume

13

1 reference

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1 November 2019

issue

6

1 reference

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1 November 2019

page(s)

1165-1168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

A Classification of Antiarrhythmic Actions Reassessed After a Decade of New Drugs

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Effects of New and Potent Methanesulfonanilide Class III Antiarrhythmic Agents on Myocardial Refractoriness and Contractility in Isolated Cardiac Muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Class III antiarrhythmic agents have a lot of potential but a long way to go. Reduced effectiveness and dangers of reverse use dependence

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

The inward rectification mechanism of the HERG cardiac potassium channel

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Evidence for two components of delayed rectifier K+ current in human ventricular myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Class III antiarrhythmic activity in vivo by selective blockade of the slowly activating cardiac delayed rectifier potassium current IKs by (R)-2-(2,4-trifluoromethyl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)- 2, 3-dihydro-1H-benzo[e][1,4]diazepin

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Design and synthesis of 4-substituted benzamides as potent, selective, and orally bioavailable I(Ks) blockers

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Synthesis and activity of novel and selective I(Ks)-channel blockers.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Inhibition of IKs in guinea pig cardiac myocytes and guinea pig IsK channels by the chromanol 293B.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

Specific blockade of slowly activating I(sK) channels by chromanols -- impact on the role of I(sK) channels in epithelia.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900049-0

7 January 2021

10.1016/S0960-894X(03)00049-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12643935%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference