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Sphingolipid hydrolases and activator proteins
scientific article published on 01 January 2000
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scholarly article
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Europe PubMed Central
PubMed publication ID
10563332
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10563332%20AND%20SRC:MED&resulttype=core&format=json
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2 November 2019
title
Sphingolipid hydrolases and activator proteins
(English)
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stated in
Europe PubMed Central
PubMed publication ID
10563332
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10563332%20AND%20SRC:MED&resulttype=core&format=json
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2 November 2019
main subject
sphingolipids
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U Bierfreund
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
10563332
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10563332%20AND%20SRC:MED&resulttype=core&format=json
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2 November 2019
T Kolter
series ordinal
2
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Europe PubMed Central
PubMed publication ID
10563332
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2 November 2019
K Sandhoff
series ordinal
3
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Europe PubMed Central
PubMed publication ID
10563332
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2 November 2019
publication date
1 January 2000
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Europe PubMed Central
PubMed publication ID
10563332
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10563332%20AND%20SRC:MED&resulttype=core&format=json
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2 November 2019
published in
Methods in Enzymology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10563332
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10563332%20AND%20SRC:MED&resulttype=core&format=json
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2 November 2019
volume
311
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10563332
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10563332%20AND%20SRC:MED&resulttype=core&format=json
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2 November 2019
page(s)
255-276
1 reference
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Europe PubMed Central
PubMed publication ID
10563332
reference URL
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2 November 2019
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Glycosphingolipids: structure, biological source, and properties
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Biological roles of oligosaccharides: all of the theories are correct
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Glycosphingolipids in cell surface recognition
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7 January 2021
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Topology of glycosphingolipid degradation
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Characterization of full-length cDNAs and the gene coding for the human GM2 activator protein
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The precursor of sulfatide activator protein is processed to three different proteins
1 reference
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Coding of two sphingolipid activator proteins (SAP-1 and SAP-2) by same genetic locus
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7 January 2021
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Structure of full-length cDNA coding for sulfatide activator, a Co-beta-glucosidase and two other homologous proteins: two alternate forms of the sulfatide activator
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Biosynthesis, processing, and targeting of sphingolipid activator protein (SAP )precursor in cultured human fibroblasts. Mannose 6-phosphate receptor-independent endocytosis of SAP precursor
1 reference
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Enzymatic diagnosis of sphingolipidoses
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Activator proteins for lysosomal glycolipid hydrolysis
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7 January 2021
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Molecular genetics of GM2-gangliosidosis AB variant: a novel mutation and expression in BHK cells
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A mutation in the gene of a glycolipid-binding protein (GM2 activator) that causes GM2-gangliosidosis variant AB
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7 January 2021
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Over-expression of a functionally active human GM2-activator protein in Escherichia coli
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Enzyme alterations and lipid storage in three variants of Tay-Sachs disease
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Complete localization of disulfide bonds in GM2 activator protein
1 reference
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7 January 2021
based on heuristic
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The complete amino-acid sequences of human ganglioside GM2 activator protein and cerebroside sulfate activator protein
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7 January 2021
based on heuristic
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Mutation in the sphingolipid activator protein 2 in a patient with a variant of Gaucher disease
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7 January 2021
based on heuristic
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Prosaposin deficiency: further characterization of the sphingolipid activator protein-deficient sibs. Multiple glycolipid elevations (including lactosylceramidosis), partial enzyme deficiencies and ultrastructure of the skin in this generalized sphi
1 reference
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7 January 2021
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Sphingolipid activator protein D (sap-D) stimulates the lysosomal degradation of ceramide in vivo
1 reference
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Saposins (sap) A and C activate the degradation of galactosylceramide in living cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids.
1 reference
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolism of GM1 ganglioside in cultured skin fibroblasts: anomalies in gangliosidoses, sialidoses, and sphingolipid activator protein (SAP, saposin) 1 and prosaposin deficient disorders
1 reference
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Preparation of radiolabeled gangliosides
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7 January 2021
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A simple and novel method for tritium labeling of gangliosides and other sphingolipids
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7 January 2021
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Activating Proteins for Ganglioside GM2Degradation by β-Hexosaminidase Isoenzymes in Tissue Extracts from Different Species
1 reference
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7 January 2021
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Purification and chemical characterization of human hexosaminidases A and B.
1 reference
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7 January 2021
based on heuristic
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59 Hexosaminidases A and B from human placenta
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and properties of human kidney-cortex hexosaminidases A and B.
1 reference
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inferred from DOI database lookup
Purification and properties of beta-hexosaminidase B from monkey brain.
1 reference
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Purification and properties of N-acetyl-β-hexosaminidases from human urine
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based on heuristic
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Complexing of Glycolipids and Their Transfer between Membranes by the Activator Protein for Degradation of Lysosomal Ganglioside GM2
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity of human liver hexosaminidases A and B against glycosphingolipids GM2 and GA2. Purification of the enzymes by affinity chromatography employing specific elution
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
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Studies on glucosaminidase. 4. The fluorimetric assay of N-acetyl-beta-glucosaminidase
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
β-Galactosidase, β-glucosidase and N-acetyl-β-glucosaminidase in human kidney
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fatty acids and sphingosine bases of porcine erythrocyte glycolipids and sphingomyelin.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glycolipids isolated from porcine intestine
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human alpha-galactosidase gene expression: significance of two peptide regions encoded by exons 1-2 and 6
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human alpha-galactosidase A: characterization of the N-linked oligosaccharides on the intracellular and secreted glycoforms overexpressed by Chinese hamster ovary cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Only sphingolipid activator protein B (SAP-B or saposin B) stimulates the degradation of globotriaosylceramide by recombinant human lysosomal alpha-galactosidase in a detergent-free liposomal system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Small-volume extrusion apparatus for preparation of large, unilamellar vesicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hydrolysis of lactosylceramide by human galactosylceramidase and GM1-beta-galactosidase in a detergent-free system and its stimulation by sphingolipid activator proteins, sap-B and sap-C. Activator proteins stimulate lactosylceramide hydrolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
pH-dependent conformational properties of saposins and their interactions with phospholipid membranes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Purified human liver acid β-d-galactosidases possessing activity towards G(M1)-ganglioside and lactosylceramide
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Direct evidence by carbon-13 NMR spectroscopy for the erythro configuration of the sphingoid moiety in Gaucher cerebroside and other natural sphingolipids
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity of human glucosylceramide beta-glucosidase towards synthetic glucosylsphingolipids inserted into liposomes. Kinetic studies in a detergent-free assay system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
56 Glucocerebrosidase from human placenta
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of heat-stable glucocerebrosidase activators from the spleens of three variants of Gaucher's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of activation of glucocerebrosidase by CO-β-glucosidase (glucosidase activator protein)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Myelination in rat brain: changes in myelin composition during brain maturation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Solubilization of glucocerebrosidase from human placenta and demonstration of a phospholipid requirement for its catalytic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glucocerebrosidase: reconstitution from macromolecular components depends on acidic phospholipids (Short Communication)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identity of 'acid' beta-glucosidase and glucocerebrosidase in human spleen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differentiation of beta-glucocerebrosidase from beta-glucosidase in human tissues using sodium taurocholate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lysosomal degradation on vesicular membrane surfaces. Enhanced glucosylceramide degradation by lysosomal anionic lipids and activators.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activator proteins and topology of lysosomal sphingolipid catabolism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Saposin D: a sphingomyelinase activator
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of saposins on acid sphingomyelinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of acid ceramidase activity by saposin D.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fluorescence reaction for amino acids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitation of free sphingosine in liver by high-performance liquid chromatography
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative correlation between the residual activity of beta-hexosaminidase A and arylsulfatase A and the severity of the resulting lysosomal storage disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Incorporation and metabolism of ganglioside GM2 in skin fibroblasts from normal and GM2 gangliosidosis subjects.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Release of Sphingomyelin Phosphodiesterase (Acid Sphingomyelinase) by Ammonium Chloride from CL 1D Mouse L-Cells and Human Fibroblasts. Partial Purification and Characterization of the Exported Enzymes
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Incorporation of ganglioside analogs into fibroblast cell membranes. A spin-label study
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prenatal Diagnosis of Metachromatic Leukodystrophy in a Family with Pseudo Arylsulfatase A Deficiency by the Cerebroside Sulfate Loading Test
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metachromatic leukodystrophy and pseudoarylsulfatase A deficiency in a Danish family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Diagnosis of metachromatic leukodystrophy, Krabbe disease, and Farber disease after uptake of fatty acid-labeled cerebroside sulfate into cultured skin fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingolipid activator protein 1 deficiency in metachromatic leucodystrophy with normal arylsulphatase A activity. A clinical, morphological, biochemical and immunological study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingolipid activator protein deficiency in a 16-week-old atypical Gaucher disease patient and his fetal sibling: biochemical signs of combined sphingolipidoses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transacylase and phospholipases in the synthesis of bis(monoacylglycero)phosphate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A lipid associated with the antiphospholipid syndrome regulates endosome structure and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glycosphingolipid degradation and animal models of GM2-gangliosidoses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunochemical characterization of two activator proteins stimulating enzymic sphingomyelin degradation in vitro. Absence of one of them in a human Gaucher disease variant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2911088-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0076-6879(00)11088-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10563332
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10563332%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
PubMed publication ID
10563332
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10563332
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10563332%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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