(Q73263614)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

Adnane J

1

1 reference

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2 November 2019

Jackson RJ

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Nicosia SV

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Cantor AB

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Pledger WJ

5

1 reference

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2 November 2019

Sebti SM

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

0 references

publication date

1 November 2000

1 reference

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2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

5338-5347

1 reference

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2 November 2019

issue

47

1 reference

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203956

2 November 2019

exact match

0 references

cites work

p21(WAF1/CIP1) is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor beta- and Sp1-responsive element: involvement of the small GTPase rhoA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Ha-ras and c-myc oncogene expression interferes with morphological and functional differentiation of mammary epithelial cells in single and double transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Functional analysis of a p21WAF1,CIP1,SDI1 mutant (Arg94 --> Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

MMTV-Fgf8 transgenic mice develop mammary and salivary gland neoplasia and ovarian stromal hyperplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

49 Rapid DNA isolations for enzymatic and hybridization analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

H-, K- and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Cell cycle: routine role for Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Relationship between Ras pathways and cell cycle control.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

p21--negative regulator of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Harderian gland hyperplasia in c-mos transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Cellular ras and cyclin D1 are required during different cell cycle periods in cycling NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Tumor spectrum analysis in p53-mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Cell cycle targets of Ras/Raf signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Activated H-ras rescues E1A-induced apoptosis and cooperates with E1A to overcome p53-dependent growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Early and multifocal tumors in breast, salivary, Harderian and epididymal tissues developed in MMTY-Neu transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Constitutive expression of the c-H-ras oncogene inhibits doxorubicin-induced apoptosis and promotes cell survival in a rhabdomyosarcoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Genetic determinants of p53-induced apoptosis and growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Strategies for improving the immunohistochemical staining of various intranuclear prognostic markers in formalin-paraffin sections: androgen receptor, estrogen receptor, progesterone receptor, p53 protein, proliferating cell nuclear antigen, and Ki-

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Transgenic mice carrying the mouse mammary tumor virus ras fusion gene: distinct effects in various tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Loss of p21CIP1/WAF1 does not recapitulate accelerated malignant conversion caused by p53 loss in experimental skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Tyrosine phosphorylation of the proto-oncoprotein Raf-1 is regulated by Raf-1 itself and the phosphatase Cdc25A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

N-myc can cooperate with ras to transform normal cells in culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021

Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203956

7 January 2021