(Q73303876)

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A steady‐state competition model describes the modulating effects of thrombomodulin on thrombin inhibition by plasminogen activator inhibitor‐1 in the absence and presence of vitronectin

scientific article published on 01 May 2003

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709053%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

A steady-state competition model describes the modulating effects of thrombomodulin on thrombin inhibition by plasminogen activator inhibitor-1 in the absence and presence of vitronectin (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709053%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

A steady‐state competition model describes the modulating effects of thrombomodulin on thrombin inhibition by plasminogen activator inhibitor‐1 in the absence and presence of vitronectin (English)

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

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based on heuristic

inferred from title

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10.1046/J.1432-1033.2003.03552.X

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26 December 2023

author name string

Hans Pannekoek

2

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Europe PubMed Central

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2 November 2019

Rob J. Dekker

1

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26 December 2023

Anton J. G. Horrevoets

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26 December 2023

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26 December 2023

publication date

1 May 2003

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2 November 2019

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26 December 2023

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1432-1033.2003.03552.x

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10.1046/J.1432-1033.2003.03552.X

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26 December 2023

https://febs.onlinelibrary.wiley.com/doi/pdf/10.1046/j.1432-1033.2003.03552.x

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

1 reference

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2 November 2019

270

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2 November 2019

1942-1951

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2 November 2019

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2 November 2019

The regulation of natural anticoagulant pathways.

1

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface

2

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Thrombin neutralizes plasminogen activator inhibitor 1 (PAI-1) that is complexed with vitronectin in the endothelial cell matrix

4

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop

6

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1

7

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Electrostatic dependence of the thrombin-thrombomodulin interaction

8

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin

9

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

10

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Effect of thrombomodulin on the kinetics of the interaction of thrombin with substrates and inhibitors

11

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Protein C inhibitor is a potent inhibitor of the thrombin-thrombomodulin complex

12

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex

13

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Expression of thrombomodulin in atherosclerotic lesions and mitogenic activity of recombinant thrombomodulin in vascular smooth muscle cells

14

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Role of exosites 1 and 2 in thrombin reaction with plasminogen activator inhibitor-1 in the absence and presence of cofactors

15

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Prothrombin-related antigens in human aortic intima

16

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Colocalization of thrombin, PAI-1, and vitronectin in the atherosclerotic vessel wall: A potential regulatory mechanism of thrombin activity by PAI-1/vitronectin complexes

17

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Inactivation of thrombin by antithrombin is accompanied by inactivation of regulatory exosite I

22

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Kinetic analysis of the interaction between type 1 plasminogen activator inhibitor and vitronectin and evidence that the bovine inhibitor binds to a thrombin-derived amino-terminal fragment of bovine vitronectin

23

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

The interaction of thrombomodulin with Ca2+

24

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Residue 225 determines the Na(+)-induced allosteric regulation of catalytic activity in serine proteases

25

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Crystal structure of the anticoagulant slow form of thrombin

26

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

The thrombin epitope recognizing thrombomodulin is a highly cooperative hot spot in exosite I.

27

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Functional requirements for inhibition of thrombin by antithrombin III in the presence and absence of heparin

28

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Thrombin interacts with thrombomodulin, protein C, and thrombin-activatable fibrinolysis inhibitor via specific and distinct domains

31

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Thrombin receptor expression in normal and atherosclerotic human arteries

33

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

The urokinase receptor is a major vitronectin-binding protein on endothelial cells

34

1 reference

10.1046/J.1432-1033.2003.03552.X

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03552.X

26 December 2023

Identifiers

10.1046/J.1432-1033.2003.03552.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709053%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709053%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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