(Q73336570)

English

Substitution of aspartic acid at beta57 with alanine alters MHC class II peptide binding activity but not protein stability: HLA-DQ (alpha10201, beta10302) and (alpha10201, beta10303)

scientific article published on 01 December 1999

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scholarly article

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Europe PubMed Central

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3 November 2019

Substitution of aspartic acid at beta57 with alanine alters MHC class II peptide binding activity but not protein stability: HLA-DQ (alpha1*0201, beta1*0302) and (alpha1*0201, beta1*0303) (English)

1 reference

Europe PubMed Central

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3 November 2019

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A K Sato

1

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3 November 2019

T Sturniolo

2

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3 November 2019

F Sinigaglia

3

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3 November 2019

L J Stern

4

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3 November 2019

publication date

1 December 1999

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3 November 2019

Human Immunology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10626736%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

60

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3 November 2019

12

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3 November 2019

1227-1236

1 reference

Europe PubMed Central

PubMed publication ID

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3 November 2019

Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study

1 reference

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HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

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Susceptibility to type I diabetes: HLA-DQ and DR revisited

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The role of MHC class II molecules in susceptibility and resistance to autoimmunity

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Genetic control of autoimmune diabetes in the NOD mouse

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7 January 2021

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Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

1 reference

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7 January 2021

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X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II

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Structures of an MHC class II molecule with covalently bound single peptides

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Crystal structure of I-Ak in complex with a dominant epitope of lysozyme

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7 January 2021

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The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

1 reference

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7 January 2021

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The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding

1 reference

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7 January 2021

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Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues

1 reference

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7 January 2021

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Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein

1 reference

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7 January 2021

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Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1 reference

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7 January 2021

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Biochemical characterization of the human diabetes-associated HLA-DQ8 allelic product: similarity to the major histocompatibility complex class II I-A(g)7 protein of non-obese diabetic mice

1 reference

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7 January 2021

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Molecular characterization of the diabetes-associated mouse MHC class II protein, I-Ag7

1 reference

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7 January 2021

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The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide

1 reference

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7 January 2021

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Empty and peptide-loaded class II major histocompatibility complex proteins produced by expression in Escherichia coli and folding in vitro.

1 reference

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7 January 2021

based on heuristic

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Stability of empty and peptide-loaded class II major histocompatibility complex molecules at neutral and endosomal pH: comparison to class I proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900120-2

7 January 2021

based on heuristic

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A conformational change in the human major histocompatibility complex protein HLA-DR1 induced by peptide binding

1 reference

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7 January 2021

based on heuristic

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Identification of two distinct properties of class II major histocompatibility complex-associated peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900120-2

7 January 2021

based on heuristic

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HLA-DQB1 codon 57 is critical for peptide binding and recognition.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900120-2

7 January 2021

based on heuristic

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Critical contribution of beta chain residue 57 in peptide binding ability of both HLA-DR and -DQ molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900120-2

7 January 2021

based on heuristic

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A peptide-binding motif for I-A(g7), the class II major histocompatibility complex (MHC) molecule of NOD and Biozzi AB/H mice

1 reference

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7 January 2021

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The peptide-binding strategy of the MHC class II I-A molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900120-2

7 January 2021

based on heuristic

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The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes-predisposing non-Aspbeta57 MHC class II molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900120-2

7 January 2021

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HLA-DC antigens can serve as recognition elements for human cytotoxic T lymphocytes

1 reference

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Structural analysis of a human I-A homologue using a monoclonal antibody that recognizes an MB3-like specificity

1 reference

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7 January 2021

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 January 2021

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inferred from DOI database lookup

Protein stability curves

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7 January 2021

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inferred from DOI database lookup

Theoretical analysis of Lumry-Eyring models in differential scanning calorimetry

1 reference

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Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules

1 reference

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7 January 2021

based on heuristic

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Production of soluble MHC class II proteins with covalently bound single peptides

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Self-peptides bound to the type I diabetes associated class II MHC molecules HLA-DQ1 and HLA-DQ8.

1 reference

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7 January 2021

based on heuristic

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Islet cell autoantigens in insulin-dependent diabetes

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Glutamic acid decarboxylase and other autoantigens in IDDM

1 reference

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Structural characterization of a soluble and partially folded class I major histocompatibility heavy chain/beta 2m heterodimer

1 reference

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Thermal stability comparison of purified empty and peptide-filled forms of a class I MHC molecule

1 reference

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The role of I-Ag7 beta chain in peptide binding and antigen recognition by T cells

1 reference

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How can cryptic epitopes trigger autoimmunity?

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Selective binding of self peptides to disease-associated major histocompatibility complex (MHC) molecules: a mechanism for MHC-linked susceptibility to human autoimmune diseases

1 reference

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Identifiers

10.1016/S0198-8859(99)00120-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10626736%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10626736%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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