(Q73356226)

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Design, synthesis and structure-activity relationship of a series of arginine aldehyde factor Xa inhibitors. Part 1: structures based on the (D)-Arg-Gly-Arg tripeptide sequence

scientific article published on 01 January 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10636232%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Design, synthesis and structure-activity relationship of a series of arginine aldehyde factor Xa inhibitors. Part 1: structures based on the (D)-Arg-Gly-Arg tripeptide sequence (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10636232%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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C K Marlowe

1

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3 November 2019

U Sinha

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10636232%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

A C Gunn

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10636232%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

R M Scarborough

4

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3 November 2019

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1 January 2000

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3 November 2019

Bioorganic & Medicinal Chemistry Letters

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3 November 2019

10

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3 November 2019

1

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3 November 2019

13-16

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3 November 2019

Coagulation factor Xa: the prothrombinase complex as an emerging therapeutic target for small molecule inhibitors

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Phosphonamidates as transition-state analogue inhibitors of thermolysin.

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Inhibition of thrombin and trypsin by tripeptide aldehydes

1 reference

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Structure-activity study of tripeptide thrombin inhibitors using alpha-alkyl amino acids and other conformationally constrained amino acid substitutions

1 reference

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Proposed cation-pi mediated binding by factor Xa: a novel enzymatic mechanism for molecular recognition.

1 reference

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Design, synthesis, and evolution of a novel, selective, and orally bioavailable class of thrombin inhibitors: P1-argininal derivatives incorporating P3-P4 lactam sulfonamide moieties

1 reference

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Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes

1 reference

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L-374,087, an efficacious, orally bioavailable, pyridinone acetamide thrombin inhibitor

1 reference

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X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition

1 reference

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Identifiers

10.1016/S0960-894X(99)00582-X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10636232%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10636232%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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