(Q73363093)

English

Ribosome targeting of PKR is mediated by two double-stranded RNA-binding domains and facilitates in vivo phosphorylation of eukaryotic initiation factor-2

scientific article published on 01 May 1997

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9162083%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Ribosome targeting of PKR is mediated by two double-stranded RNA-binding domains and facilitates in vivo phosphorylation of eukaryotic initiation factor-2 (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9162083%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

S Zhu

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9162083%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

P R Romano

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9162083%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

R C Wek

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9162083%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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1 May 1997

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3 November 2019

Journal of Biological Chemistry

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9162083%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

272

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3 November 2019

22

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3 November 2019

14434-14441

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9162083%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

A conserved double-stranded RNA-binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Protein-RNA recognition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Conserved structures and diversity of functions of RNA-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Cytochrome f revealed.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

eIF-2 kinases: regulators of general and gene-specific translation initiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

The eIF-2 alpha kinases: regulators of protein synthesis in starvation and stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Translational control in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Control of translation initiation in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

The double-stranded RNA-dependent protein kinase is also activated by heparin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Mechanism of interferon action motif I of the interferon-induced, RNA-dependent protein kinase (PKR) is sufficient to mediate RNA-binding activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Two functionally distinct RNA-binding motifs in the regulatory domain of the protein kinase DAI

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Mutational analysis of the double-stranded RNA (dsRNA) binding domain of the dsRNA-activated protein kinase, PKR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Purification of double-stranded RNA-dependent protein kinase from mouse fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Localization of Epstein-Barr virus-encoded RNAs EBER-1 and EBER-2 in interphase and mitotic Burkitt lymphoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Nuclear localization of the interferon-inducible protein kinase PKR in human cells and transfected mouse cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Blockage of NF-kappa B signaling by selective ablation of an mRNA target by 2-5A antisense chimeras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Casein kinase II mediates multiple phosphorylation of Saccharomyces cerevisiae eIF-2 alpha (encoded by SUI2), which is required for optimal eIF-2 function in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

The highly acidic C-terminal region of the yeast initiation factor subunit 2 alpha (eIF-2 alpha) contains casein kinase phosphorylation sites and is essential for maintaining normal regulation of GCN4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Lesions and virus accumulation in inoculated transgenic tobacco plants expressing the coat protein gene of tobacco mosaic virus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Ribosome association of GCN2 protein kinase, a translational activator of the GCN4 gene of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Assignment of the backbone 1H,15N,13C NMR resonances and secondary structure of a double-stranded RNA binding domain from the Drosophila protein staufen.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

More on target with protein phosphorylation: conferring specificity by location

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Activation of the double-stranded RNA (dsRNA)-activated human protein kinase in vivo in the absence of its dsRNA binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

The structure and regulation of protein phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Mitochondrial ribosomes of yeast: isolation of individual proteins and N-terminal sequencing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14434

21 January 2018

Identifiers

10.1074/JBC.272.22.14434

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9162083%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9162083%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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