(Q73372705)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

[3H]tiagabine binding to GABA uptake sites in human brain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

I S Eriksson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

P Allard

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

J Marcusson

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

publication date

1 December 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

851

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

1-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

183-188

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate

3 November 2019

cites work

1 reference

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Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902183-6

GABA transporter heterogeneity: pharmacology and cellular localization

7 January 2021

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Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies

7 January 2021

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Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranes

7 January 2021

1 reference

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(R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902183-6

Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortex

7 January 2021

1 reference

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Localization of messenger RNAs encoding three GABA transporters in rat brain: an in situ hybridization study

7 January 2021

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Cloning and expression of a rat brain GABA transporter

7 January 2021

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GABA synaptic mechanisms: stereochemical and conformational requirements

7 January 2021

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A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

7 January 2021

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Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC.

7 January 2021

1 reference

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Synthesis of γ-aminobutyric acid from a pool of glutamic acid in brain after decapitation

7 January 2021

1 reference

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GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex.

7 January 2021

1 reference

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LIGAND: A versatile computerized approach for characterization of ligand-binding systems

7 January 2021

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Distribution of GABA-T-intensive neurons in the rat forebrain and midbrain

7 January 2021

1 reference

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Cloning of the human brain GABA transporter

7 January 2021

1 reference

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Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902183-6

3Hnipecotic acid binding to GABA uptake sites in human brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902183-6

In vivo labeling of the central GABA uptake carrier with 3H-Tiagabine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902183-6

Quantitative autoradiographic characterization of the binding of [3H]tiagabine (NNC 05-328) to the GABA uptake carrier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902183-6

A review of the preclinical pharmacology of tiagabine: a potent and selective anticonvulsant GABA uptake inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902183-6

Simultaneous liquid chromatographic determination of seventeen of the major monoamine neurotransmitters, precursors and metabolites. II. Assessment of human brain and cerebrospinal fluid concentrations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902183-6

Regional distribution of GABA transporter 1 (GAT1) mRNA in the rat brain: comparison with glutamic acid decarboxylase67 (GAD67) mRNA localization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902183-6

10.1016/S0006-8993(99)02183-6

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10642842%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference