(Q73393601)

English

The pathobiology of focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis

scientific article published on 01 May 2003

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12746899%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

The pathobiology of focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12746899%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

author name string

Sharon Okouneff

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12746899%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Mirela Ionescu

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12746899%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Ginette R. Squires

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12746899

2 January 2024

A. Robin Poole

4

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Europe PubMed Central

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2 January 2024

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12746899

2 January 2024

publication date

1 May 2003

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Europe PubMed Central

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3 November 2019

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https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fart.10976

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

https://onlinelibrary.wiley.com/doi/pdf/10.1002/art.10976

1 reference

10.1002/ART.10976

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2 January 2024

Arthritis and Rheumatism

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12746899%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

48

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Europe PubMed Central

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3 November 2019

5

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Europe PubMed Central

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3 November 2019

1261-1270

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12746899%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage

3

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Collagen synthesis in normal and osteoarthritic human cartilage

4

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Activation of fibrillar collagen synthesis and phenotypic modulation of chondrocytes in early human osteoarthritic cartilage lesions

5

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Evidence for altered synthesis of type II collagen in patients with osteoarthritis

6

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease

7

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

10

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage

11

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration

12

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay

13

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

In vivo and in vitro stimulation of chondrocyte biosynthetic activity in early experimental osteoarthritis

14

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Expression of proteoglycans and collagen in the hypertrophic phase of experimental osteoarthritis

15

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

The early molecular natural history of experimental osteoarthritis. I. Progressive discoordinate expression of aggrecan and type II procollagen messenger RNA in the articular cartilage of adult animals

17

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Articular cartilage superficial zone collagen birefringence reduced and cartilage thickness increased before surface fibrillation in experimental osteoarthritis

18

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis

19

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Type II collagen degradation in spontaneous osteoarthritis in C57Bl/6 and BALB/c mice

20

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1)

22

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

In situ zymographic localisation of type II collagen degrading activity in osteoarthritic human articular cartilage

23

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue.

25

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

A simple, rapid, and sensitive DNA assay procedure

26

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Immunohistochemical detection and immunochemical analysis of type II collagen degradation in human normal, rheumatoid, and osteoarthritic articular cartilages and in explants of bovine articular cartilage cultured with interleukin 1

28

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

The increased swelling and instantaneous deformation of osteoarthritic cartilage is highly correlated with collagen degradation

29

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Discoordinate gene expression of aggrecan and type II collagen in experimental osteoarthritis

30

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Cartilage hypertrophy following canine anterior cruciate ligament transection differs among different areas of the joint

31

1 reference

10.1002/ART.10976

https://api.crossref.org/works/10.1002/ART.10976

2 January 2024

Identifiers

10.1002/ART.10976

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12746899%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12746899%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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