(Q73401718)

English

The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis

scientific article published on 01 February 2000

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scholarly article

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3 November 2019

The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis (English)

1 reference

Europe PubMed Central

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3 November 2019

apoptotic process

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author name string

Roberts RA

1

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3 November 2019

James NH

2

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3 November 2019

Cosulich SC

3

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3 November 2019

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1 February 2000

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3 November 2019

1 reference

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3 November 2019

31

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3 November 2019

2

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3 November 2019

420-427

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3 November 2019

Liver regeneration

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Liver regeneration. 2. Role of growth factors and cytokines in hepatic regeneration

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Dysregulation of apoptosis in hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Epidermal growth factor, but not hepatocyte growth factor, suppresses the apoptosis induced by transforming growth factor-beta in fetal hepatocytes in primary culture

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogen-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Uncoupling of hepatic, epidermal growth factor-mediated mitogen-activated protein kinase activation in the fetal rat

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms of impaired stimulation of DNA synthesis in cultured hepatocytes of aged rats

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Positive and negative regulation of JNK1 by protein kinase C and p42(MAP kinase) in adult rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor receptor-mediated signaling pathways

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor primes hepatocytes for DNA replication in the rat

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytokines in non-genotoxic hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of liver regeneration in mice lacking type 1 or type 2 tumor necrosis factor receptor: requirement for type 1 but not type 2 receptor

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Delayed Fas-mediated hepatocyte apoptosis during liver regeneration in mice: hepatoprotective role of TNF alpha.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Role for tumor necrosis factor alpha receptor 1 and interleukin-1 receptor in the suppression of mouse hepatocyte apoptosis by the peroxisome proliferator nafenopin

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Hepatocyte apoptosis and hepatic expression of transforming growth factor-beta1 mRNA during involution of hyperplastic rat liver induced by hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of rat hepatocyte proliferation by transforming growth factor beta and glucagon is associated with inhibition of ERK2 and p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis Induced by Transforming Growth Factor- in Fetal Hepatocyte Primary Cultures

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of apoptosis in cultured hepatocytes and in the regressing liver by transforming growth factor-beta 1 occurs without activation of an endonuclease

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced expression of mature TGF beta 1 correlates with the suppression of rat hepatocyte apoptosis by the peroxisome proliferator, nafenopin

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumour necrosis factor alpha (TNF alpha) suppresses apoptosis and induces DNA synthesis in rodent hepatocytes: a mediator of the hepatocarcinogenicity of peroxisome proliferators?

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of transforming growth factor-beta-induced apoptosis through a phosphatidylinositol 3-kinase/Akt-dependent pathway

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential regulation of the mitogen-activated protein and stress-activated protein kinase cascades by adrenergic agonists in quiescent and regenerating adult rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Response to transforming growth factor alpha (TGFalpha) and epidermal growth factor (EGF) in hepatocytes: lower EGF receptor affinity of TGFalpha is associated with more sustained activation of p42/p44 mitogen-activated protein kinase and greater ef

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

SB202190, a selective inhibitor of p38 mitogen-activated protein kinase, is a powerful regulator of LPS-induced mRNAs in monocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of human cytokine production and effects of pharmacological agents in a heterologous system in vivo

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510310223

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/HEP.510310223

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10655266%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10655266%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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