(Q73408062)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Conjugation-deconjugation cycling of diflunisal via beta-glucuronidase catalyzed hydrolysis of its acyl glucuronide in the rat (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

F M Brunelle

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

R K Verbeeck

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

language of work or name

English

0 references

publication date

1 January 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

60

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

2013-2021

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation

3 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

7 January 2021

1 reference

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Futile cycling between 4-methylumbelliferone and its conjugates in perfused rat liver

7 January 2021

1 reference

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The conjugative metabolism of 4-methylumbelliferone and deconjugation to the parent drug examined by isolated perfused liver and in vitro liver homogenate of rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Stimulation of 3-benzo[a]pyrenyl glucuronide hydrolysis by calcium activation of microsomal beta-glucuronidase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Glucuronidation of diflunisal by rat liver microsomes. Effect of microsomal beta-glucuronidase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Elimination of diflunisal as its acyl glucuronide, phenolic glucuronide and sulfate conjugates in bile-exteriorized and intact rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

The preparation and properties of beta-glucuronidase. IV. Inhibition by sugar acids and their lactones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

D-glucaro-1,4-lactone: its excretion in the bile and urine and effect on the biliary secretion of beta-glucuronidase after oral administration in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Evidence that d-glucaro-1,4-lactone shortens the pharmacological action of drugs being disposed via the bile as glucuronides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

High-performance liquid chromatographic method for the simultaneous quantitation of diflunisal and its glucuronide and sulfate conjugates in human urine

7 January 2021

1 reference

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Studies in detoxication. 67. The biosynthesis of the glucuronides of umbelliferone and 4-methylumbelliferone and their use in fluorimetric determination of beta-glucuronidase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Analytical study of microsomes and isolated subcellular membranes from rat liver. II. Preparation and composition of the microsomal fraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Reactivity considerations in the analysis of glucuronide and sulfate conjugates of diflunisal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Absence of phenolic glucuronidation and enhanced hydroxylation of diflunisal in the homozygous Gunn rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Hepatic conjugation/deconjugation cycling pathways. Computer simulations examining the effect of Michaelis-Menten parameters, enzyme distribution patterns, and a diffusional barrier on metabolite disposition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Does deconjugation of bilirubin glucuronide occur in obstructive jaundice?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Deconjugation of bilirubin glucuronide by the liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Acyl glucuronides revisited: is the glucuronidation process a toxification as well as a detoxification mechanism?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Studies on the reactivity of acyl glucuronides--V. Glucuronide-derived covalent binding of diflunisal to bladder tissue of rats and its modulation by urinary pH and beta-glucuronidase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

Vesico-hepato-renal cycling of acidic drugs via their reactive acyl glucuronide metabolites? Studies with diflunisal in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2897%2900166-5

10.1016/S0024-3205(97)00166-5

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9180355%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference