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English
Screening lead compounds for QT interval prolongation
scientific article published on 01 January 2001
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
Screening lead compounds for QT interval prolongation
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
lead
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inferred from title
author name string
R Netzer
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
A Ebneth
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
U Bischoff
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
O Pongs
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
publication date
1 January 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Drug Discovery Today
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
78-84
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
QT-interval prolongation by non-cardiac drugs: lessons to be learned from recent experience
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acquired QT Prolongation: Mechanisms and Implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dysfunction of delayed rectifier potassium channels in an inherited cardiac arrhythmia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ion channels--basic science and clinical disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preclinical in vitro cardiac electrophysiology: a method of predicting arrhythmogenic potential of antihistamines in humans?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cardiac ion channels: relevance to management of arrhythmias
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drugs that prolong QT interval as an unwanted effect: assessing their likelihood of inducing hazardous cardiac dysrhythmias
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular genetics of long-QT syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Time course and voltage dependence of expressed HERG current compared with native "rapid" delayed rectifier K current during the cardiac ventricular action potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid inactivation determines the rectification and [K+]o dependence of the rapid component of the delayed rectifier K+ current in cardiac cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiac ion channels and antihistamines: possible mechanisms of cardiotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of H1 antihistamines on animal models of QTc prolongation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Experimental models of torsade de pointes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of ketoconazole in the QTc interval prolonging effects of H1-antihistamines in a guinea-pig model of arrhythmogenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
QT interval prolongation by non-cardiovascular drugs: issues and solutions for novel drug development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of endogenous outward currents in the human embryonic kidney (HEK 293) cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the steady-state and dynamic fluorescence properties of the potential-sensitive dye bis-(1,3-dibutylbarbituric acid)trimethine oxonol (Dibac4(3)) in model systems and cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-based assays and instrumentation for screening ion-channel targets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901602-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1359-6446(00)01602-0
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed publication ID
11166255
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166255
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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