(Q73442683)

English

Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two thrombin-inhibitor complexes

scientific article published on 01 April 1997

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9195869%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two thrombin-inhibitor complexes (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9195869%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

U Obst

1

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4 November 2019

D W Banner

2

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4 November 2019

L Weber

3

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4 November 2019

F Diederich

4

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4 November 2019

publication date

1 April 1997

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4 November 2019

Chemistry and Biology

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4 November 2019

4

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4 November 2019

4

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4 November 2019

287-295

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4 November 2019

Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors

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The action of thrombin on peptide p-nitroanilide substrates: hydrolysis of Tos-Gly-Pro-Arg-pNA and D-Phe-Pip-Arg-pNA by human alpha and gamma and bovine alpha and beta-thrombins

1 reference

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Design and synthesis of potent and highly selective thrombin inhibitors

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Hydrogen bonding and biological specificity analysed by protein engineering

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Identifiers

10.1016/S1074-5521(97)90072-7

1 reference

Europe PubMed Central

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4 November 2019

1 reference

Europe PubMed Central

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4 November 2019

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