(Q73442739)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9195929%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Intrinsic specificity of the reactive site loop of alpha1-antitrypsin, alpha1-antichymotrypsin, antithrombin III, and protease nexin I (English)

1 reference

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4 November 2019

3

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4 November 2019

author name string

M Z Djie

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9195929%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

S R Stone

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9195929%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

language of work or name

English

0 references

publication date

1 June 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9195929%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

4 November 2019

published in

1 reference

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4 November 2019

volume

272

1 reference

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4 November 2019

issue

26

1 reference

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4 November 2019

page(s)

16268-16273

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9195929%20AND%20SRC:MED&resulttype=core&format=json

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

4 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Natural protein proteinase inhibitors and their interaction with proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Mutation of antitrypsin to antithrombin. alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

P1 variant antithrombins Glasgow (393 Arg to His) and Pescara (393 Arg to Pro) have increased heparin affinity and are resistant to catalytic cleavage by elastase. Implications for the heparin activation mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Divining the serpin inhibition mechanism: a suicide substrate 'springe'?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Human plasma proteinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Sequence homology between human alpha 1-antichymotrypsin, alpha 1-antitrypsin, and antithrombin III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Met 358 to Arg mutation of alpha 1-antitrypsin associated with protein C deficiency in a patient with mild bleeding tendency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Interaction of activated protein C with serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Glial-derived neurite-promoting factor is a slow-binding inhibitor of trypsin, thrombin, and urokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Localization of the heparin-binding site of glia-derived nexin/protease nexin-1 by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Kinetics of the inhibition of thrombin by hirudin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Conversion of alpha 1-antichymotrypsin into a human neutrophil elastase inhibitor: demonstration of variants with different association rate constants, stoichiometries of inhibition, and complex stabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Role of the P2 residue in determining the specificity of serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

The action of thrombin on peptide p-nitroanilide substrates. Substrate selectivity and examination of hydrolysis under different reaction conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Kinetics of suicide substrates. Practical procedures for determining parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Inhibitory mechanism of serpins. Interaction of thrombin with antithrombin and protease nexin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

The contribution of the conserved hinge region residues of alpha1-antitrypsin to its reaction with elastase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Site-directed mutagenesis of the P2 residue of human antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Kinetic characterization of the proteinase binding defect in a reactive site variant of the serpin, antithrombin. Role of the P1' residue in transition-state stabilization of antithrombin-proteinase complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Development of a novel recombinant serpin with potential antithrombotic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Identification of thrombin residues that modulate its interactions with antithrombin III and alpha 1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Effect of alanine insertion (P'5) on the reactive centre of alpha 1-antitrypsin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Identification of lysines within alpha 1-antichymotrypsin important for DNA binding. An unusual combination of DNA-binding elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Protein inhibitors of proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Refined 2.5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination, refinement, structure and comparison with its [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Directed evolution of a protein: selection of potent neutrophil elastase inhibitors displayed on M13 fusion phage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Potent and Selective Kunitz Domain Inhibitors of Plasma Kallikrein Designed by Phage Display

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Crystal and molecular structure of the bovine α-chymotrypsin-eglin c complex at 2.0 Å resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Changing the inhibitory specificity and function of the proteinase inhibitor eglin c by site-directed mutagenesis: functional and structural investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Crystal structure of an uncleaved alpha 1-antitrypsin reveals the conformation of its inhibitory reactive loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Inhibitory conformation of the reactive loop of alpha 1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

Organization of serpin gene-1 from Manduca sexta. Evolution of a family of alternate exons encoding the reactive site loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.26.16268

21 January 2018

Identifiers

DOI

10.1074/JBC.272.26.16268

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9195929%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference