(Q73499740)

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Phase I and pharmacologic study of the human DNA methyltransferase antisense oligodeoxynucleotide MG98 given as a 21-day continuous infusion every 4 weeks

scientific article published on 01 February 2003

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12795533%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Phase I and pharmacologic study of the human DNA methyltransferase antisense oligodeoxynucleotide MG98 given as a 21-day continuous infusion every 4 weeks (English)

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Europe PubMed Central

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4 November 2019

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Alison J Davis

1

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4 November 2019

Karen A Gelmon

2

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4 November 2019

Lillian L Siu

3

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4 November 2019

Malcolm J Moore

4

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4 November 2019

Carolyn D Britten

5

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4 November 2019

Nisha Mistry

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4 November 2019

Henry Klamut

7

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4 November 2019

Susan D'Aloisio

8

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4 November 2019

Martha MacLean

9

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4 November 2019

Nancy Wainman

10

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4 November 2019

Debbie Ayers

11

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4 November 2019

Patricia Firby

12

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4 November 2019

Jeffrey M Besterman

13

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4 November 2019

Gregory K Reid

14

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4 November 2019

Elizabeth A Eisenhauer

15

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4 November 2019

publication date

1 February 2003

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4 November 2019

Investigational New Drugs

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Europe PubMed Central

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4 November 2019

21

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4 November 2019

1

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4 November 2019

85-97

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4 November 2019

https://scigraph.springernature.com/pub.10.1023/a:1022976528441

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DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe.

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Modified deoxyoligonucleotides stable to exonuclease degradation in serum

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Mouse DNA methylase: Methylation of native DNA

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Fetal hemoglobin gene activation in a phase II study of 5,6-dihydro-5-azacytidine for bronchogenic carcinoma

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The DNA methylation paradox

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Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides

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The DNA methylation machinery as a target for anticancer therapy

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Antisense oligonucleotide inhibitors for the treatment of cancer: 1. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides.

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Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a four-week study in cynomolgus monkeys.

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

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