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HPV E6 targeted degradation of the discs large protein: evidence for the involvement of a novel ubiquitin ligase
scientific article published on 01 February 2000
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1 reference
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Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
title
HPV E6 targeted degradation of the discs large protein: evidence for the involvement of a novel ubiquitin ligase
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author name string
D Pim
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
M Thomas
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2
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Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
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4 November 2019
R Javier
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3
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Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
D Gardiol
series ordinal
4
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Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
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4 November 2019
L Banks
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5
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Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
language of work or name
English
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publication date
1 February 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
published in
Oncogene
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stated in
Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
volume
19
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Europe PubMed Central
PubMed publication ID
10698489
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4 November 2019
issue
6
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Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
page(s)
719-725
1 reference
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Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
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4 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1203374
0 references
cites work
Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines.
1 reference
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Crossref
reference URL
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Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomas
1 reference
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Possible prognostic significance of human papillomavirus type in cervical cancer
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Prognostic significance of polymerase chain reaction detected human papillomavirus of tumors and lymph nodes in surgically treated stage IB cervical cancer
1 reference
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7 January 2021
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Sensitivity of p53 lysine mutants to ubiquitin-directed degradation targeted by human papillomavirus E6
1 reference
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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
1 reference
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Comparison of human papillomavirus type 18 (HPV-18) E6-mediated degradation of p53 in vitro and in vivo reveals significant differences based on p53 structure and cell type but little difference with respect to mutants of HPV-18 E6.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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Comparative study on E6 and E7 genes of some cutaneous and genital papillomaviruses of human origin for their ability to transform 3Y1 cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dispensability of p53 degradation for tumorigenicity and decreased serum requirement of human papillomavirus type 16 E6.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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Degradation of p53 only is not sufficient for the growth stimulatory effect of human papillomavirus 16 E6 oncoprotein in human embryonic fibroblasts.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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Plasma membrane Ca2+ ATPase isoform 4b binds to membrane-associated guanylate kinase (MAGUK) proteins via their PDZ (PSD-95/Dlg/ZO-1) domains
1 reference
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Crossref
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7 January 2021
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Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases
1 reference
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Crossref
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7 January 2021
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Polarized signaling: basolateral receptor localization in epithelial cells by PDZ-containing proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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inferred from DOI database lookup
Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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Analysis of individual human papillomavirus types in cervical neoplasia: a possible role for type 18 in rapid progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modular organization of the PDZ domains in the human discs-large protein suggests a mechanism for coupling PDZ domain-binding proteins to ATP and the membrane cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells.
1 reference
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Crossref
reference URL
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7 January 2021
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Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.
1 reference
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Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein
1 reference
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Crossref
reference URL
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7 January 2021
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Mutational analysis of human papillomavirus type 16 E6 protein: transforming function for human cells and degradation of p53 in vitro
1 reference
stated in
Crossref
reference URL
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7 January 2021
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HPV-18 E6*I protein modulates the E6-directed degradation of p53 by binding to full-length HPV-18 E6.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternatively spliced HPV-18 E6* protein inhibits E6 mediated degradation of p53 and suppresses transformed cell growth
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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DHR domains in syntrophins, neuronal NO synthases and other intracellular proteins
1 reference
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7 January 2021
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PDZ domains bind carboxy-terminal sequences of target proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
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inferred from DOI database lookup
Structure and transcription of human papillomavirus sequences in cervical carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in transformation activity between HPV-18 and HPV-16 map to the viral LCR-E6-E7 region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
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inferred from DOI database lookup
Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
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inferred from DOI database lookup
Association of human papillomavirus types 16 and 18 E6 proteins with p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Associations between oncogenic human papillomaviruses and local invasive patterns in cervical cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
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inferred from DOI database lookup
Human papillomaviruses in the pathogenesis of anogenital cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203374
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1203374
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
Dimensions Publication ID
1033023106
0 references
PubMed publication ID
10698489
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10698489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10698489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
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