(Q73520977)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9228093%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Residues flanking the HOX YPWM motif contribute to cooperative interactions with PBX (English)

1 reference

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4 November 2019

2

1 reference

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4 November 2019

author name string

K Shanmugam

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9228093%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

H U Saragovi

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9228093%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

language of work or name

English

0 references

publication date

1 July 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9228093%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

4 November 2019

number of pages

7

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9228093%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

volume

272

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9228093%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9228093%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

page(s)

19081-19087

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9228093%20AND%20SRC:MED&resulttype=core&format=json

Homeobox genes and axial patterning

4 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Hox genes in vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Early mouse development: lessons from gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

The murine and Drosophila homeobox gene complexes have common features of organization and expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Homeodomain-DNA recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Differential and stage-related expression in embryonic tissues of a new human homoeobox gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

NMR structure determination reveals that the homeodomain is connected through a flexible linker to the main body in the Drosophila Antennapedia protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Extradenticle protein is a selective cofactor for the Drosophila homeotics: role of the homeodomain and YPWM amino acid motif in the interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

extradenticle raises the DNA binding specificity of homeotic selector gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain--demonstration of Hox-dependent targeting of E2a-Pbx1 in viv

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Distinct HOX N-terminal arm residues are responsible for specificity of DNA recognition by HOX monomers and HOX.PBX heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

A strategy for generating monoclonal antibodies against recombinant baculovirus-produced proteins: application to the Bcl-2 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.19081

21 January 2018

Identifiers

DOI

10.1074/JBC.272.30.19081

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9228093%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference