(Q73553429)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Alpha-phenyl-tert-butylnitrone (PBN) inhibits NFkappaB activation offering protection against chemically induced diabetes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

E Ho

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

G Chen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

T M Bray

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

publication date

1 February 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

Free Radical Biology and Medicine

4 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

page(s)

604-614

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

Inheritance of diabetes mellitus

4 November 2019

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A solution to the genetic and environmental puzzles of insulin-dependent diabetes mellitus

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Free radicals and diabetes

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Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation

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Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM

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7 January 2021

Alloxan-induced diabetes-evidence for hydroxyl radical as a cytotoxic intermediate

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7 January 2021

Generation of nitric oxide from streptozotocin (STZ) in the presence of copper(II) plus ascorbate: implication for the development of STZ-induced diabetes

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7 January 2021

Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotozin contributes to islet cell DNA damage.

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7 January 2021

Nitric oxide generation from streptozotocin

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Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

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7 January 2021

Structure, regulation and function of NF-kappa B

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The NF-kappa B and I kappa B proteins: new discoveries and insights

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Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.

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Kappa B-specific DNA binding proteins: role in the regulation of human interleukin-2 gene expression

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7 January 2021

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor

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7 January 2021

Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

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7 January 2021

Spin trapping agent, phenyl N-tert-butyl nitrone, inhibits induction of nitric oxide synthase in endotoxin-induced shock in mice

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7 January 2021

Protection against oxidative damage to CNS by α-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: A novel series of nonlipid free radical scavengers

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7 January 2021

Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress

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7 January 2021

Low dose streptozotocin induced diabetes in mice. Metabolic, light microscopical, histochemical, immunofluorescence microscopical, electron microscopical and morphometrical findings

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7 January 2021

[25] Nitric-oxide synthase assays

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7 January 2021

Supplementation of N-acetylcysteine inhibits NFkappaB activation and protects against alloxan-induced diabetes in CD-1 mice.

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7 January 2021

Evidence for involvement of the proteasome complex (26S) and NFkappaB in IL-1beta-induced nitric oxide and prostaglandin production by rat islets and RINm5F cells

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7 January 2021

Excretion, metabolism and tissue distribution of a spin trapping agent, alpha-phenyl-N-tert-butyl-nitrone (PBN) in rats

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7 January 2021

Alloxan toxicity to the pancreatic B-cell. A new hypothesis

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7 January 2021

Determinants of the selective toxicity of alloxan to the pancreatic B cell

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7 January 2021

Metal-mediated DNA damage induced by diabetogenic alloxan in the presence of NADH.

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7 January 2021

Stabilities of hydroxyl radical spin adducts of PBN-type spin traps☆

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7 January 2021

Superoxide dismutase is a prophylactic against alloxan diabetes

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7 January 2021

Effect of superoxide dismutase, catalase, chelating agents, and free radical scavengers on the toxicity of alloxan to isolated pancreatic islets in vitro

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7 January 2021

DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin

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7 January 2021

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

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7 January 2021

Spin trapping agent phenyl N-tert-butylnitrone protects against the onset of drug-induced insulin-dependent diabetes mellitus

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7 January 2021

Inhibition of NF-kappaB, iNOS mRNA, COX2 mRNA, and COX catalytic activity by phenyl-N-tert-butylnitrone (PBN).

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7 January 2021

Nuclear factor kappa B: important transcription factor and therapeutic target

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7 January 2021

Oxidants, transcription factors, and intestinal inflammation.

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7 January 2021

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

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7 January 2021

NF-kappa B activation in human knee-joint synovial tissue during the early stage of joint inflammation

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7 January 2021

Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation

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7 January 2021

Cyclosporine A is an uncompetitive inhibitor of proteasome activity and prevents NF-kappaB activation.

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7 January 2021

Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IkappaB alpha phosphorylation and degradation

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7 January 2021

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference