(Q73556819)

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Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury

scientific article published on 01 March 2000

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5 November 2019

Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury (English)

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5 November 2019

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A D Bennett

1

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5 November 2019

A W Everhart

2

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5 November 2019

C E Hulsebosch

3

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5 November 2019

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1 March 2000

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5 November 2019

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5 November 2019

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5 November 2019

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5 November 2019

72-82

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5 November 2019

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Alleviation of mechanical and thermal allodynia by CGRP(8-37) in a rodent model of chronic central pain

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Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation

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Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain

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Mechanical and thermal allodynia in chronic central pain following spinal cord injury

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Chronic central pain after spinal cord injury

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Spinal cord injury and anti-NGF treatment results in changes in CGRP density and distribution in the dorsal horn in the rat

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Contribution of protein kinase C to central sensitization and persistent pain following tissue injury

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Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence

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The utility of excitatory amino acid (EAA) antagonists as analgesic agents. I. Comparison of the antinociceptive activity of various classes of EAA antagonists in mechanical, thermal and chemical nociceptive tests.

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7 January 2021

Receptor localization in the mammalian dorsal horn and primary afferent neurons

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7 January 2021

Function-limiting dysesthetic pain syndrome among traumatic spinal cord injury patients: a cross-sectional study

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7 January 2021

Evidence for involvement of N-methylaspartate receptors in 'wind-up' of class 2 neurones in the dorsal horn of the rat.

1 reference

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7 January 2021

Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation

1 reference

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7 January 2021

Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat

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7 January 2021

The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli

1 reference

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7 January 2021

Neural changes in acute arthritis in monkeys. I. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids

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7 January 2021

Modification of the responses of primate spinothalamic neurons to mechanical stimulation by excitatory amino acids and an N-methyl-D-aspartate antagonist.

1 reference

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7 January 2021

Enhancement of spinothalamic neuron responses to chemical and mechanical stimuli following combined micro-iontophoretic application of N-methyl-D-aspartic acid and substance P.

1 reference

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7 January 2021

Central dysesthesia pain after traumatic spinal cord injury is dependent on N-methyl-D-aspartate receptor activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902483-X

7 January 2021

Antinociception induced by 3-((+-)-2-carboxypiperazin-4-yl)-propyl-1- phosphonic acid (CPP), an N-methyl-D-aspartate (NMDA) competitive antagonist, plus 6,7-dinitroquinoxaline-2,3-dione (DNQX), a non-NMDA antagonist, differs from that induced by MK-

1 reference

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7 January 2021

Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered nitric oxide synthase inhibitors

1 reference

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7 January 2021

The excitatory amino acid receptor antagonist MK-801 prevents the hypersensitivity induced by spinal cord ischemia in the rat

1 reference

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7 January 2021

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

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7 January 2021

A model of peripheral mononeuropathy in the rat

1 reference

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Sprouting of dorsal root axons

1 reference

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7 January 2021

Sprouting of primary afferent fibers after spinal cord transection in the rat.

1 reference

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7 January 2021

Spinal cord morphology and antinociception after chronic intrathecal administration of excitatory amino acid antagonists in the rat.

1 reference

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Characteristics of somatotopic organization and spontaneous neuronal activity in the region of the thalamic principal sensory nucleus in patients with spinal cord transection

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7 January 2021

Windup leads to characteristics of central sensitization

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7 January 2021

Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn

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7 January 2021

Antinociceptive effects of NMDA and non-NMDA receptor antagonists in the tail flick test in mice

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7 January 2021

Noxious stimuli induce an N-methyl-D-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: implications for the treatment of mechanical allodynia.

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7 January 2021

Denervation-induced intraspinal synaptogenesis of calcitonin gene-related peptide containing primary afferent terminals

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Intraspinal sprouting of calcitonin gene-related peptide containing primary afferents after deafferentation in the rat

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Production of endogenous nitric oxide and activation of soluble guanylate cyclase are required for N-methyl-D-aspartate-produced facilitation of the nociceptive tail-flick reflex

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Antinociceptive actions of different classes of excitatory amino acid receptor antagonists in mice

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Effects of intrathecal NMDA and non-NMDA antagonists on acute thermal nociception and their interaction with morphine

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Intrathecal N-methyl-D-aspartate (NMDA) activates both nociceptive and antinociceptive systems.

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Identifiers

10.1016/S0006-8993(99)02483-X

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720616%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720616%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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