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Interleukin-6 sensitizes multiple myeloma cell lines for apoptosis induced by interferon-alpha
scientific article published on 01 March 2000
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
title
Interleukin-6 sensitizes multiple myeloma cell lines for apoptosis induced by interferon-alpha
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
main subject
multiple myeloma
1 reference
based on heuristic
inferred from title
author name string
R Minami
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
K Muta
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
C Ilseung
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
Y Abe
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
J Nishimura
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
H Nawata
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
publication date
1 March 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
published in
Experimental Hematology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
28
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
244-255
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
cites work
Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential myeloma cell responsiveness to interferon-alpha correlates with differential induction of p19(INK4d) and cyclin D2 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon-alpha down-regulates the interleukin-6 receptor in a human multiple myeloma cell line, U266.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-xL acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two CD95 (APO-1/Fas) signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-6 inhibits apoptosis of malignant plasma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated entry into S phase associated with up-regulation of cyclin D1 as a mechanism for granulocyte colony-stimulating factor (G-CSF)-induced apoptosis of murine myeloid leukemia cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Maintenance by erythropoietin of viability and maturation of murine erythroid precursor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis of human erythroid colony-forming cells is decreased by stem cell factor and insulin-like growth factor I as well as erythropoietin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A hamster temperature-sensitive G1 mutant, tsBN250 has a single point mutation in histidyl-tRNA synthetase that inhibits an accumulation of cyclin D1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol-3-OH kinase as a direct target of Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-472X%2899%2900156-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0301-472X(99)00156-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed publication ID
10720689
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10720689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10720689%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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