(Q73567230)

English

p53-degradation by HPV-16 E6 preferentially affects the removal of cyclobutane pyrimidine dimers from non-transcribed strand and sensitizes mammary epithelial cells to UV-irradiation

scientific article published on 01 March 2000

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5 November 2019

p53-degradation by HPV-16 E6 preferentially affects the removal of cyclobutane pyrimidine dimers from non-transcribed strand and sensitizes mammary epithelial cells to UV-irradiation (English)

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5 November 2019

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M A El-Mahdy

1

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5 November 2019

F M Hamada

2

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5 November 2019

M A Wani

3

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5 November 2019

Q Zhu

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5 November 2019

A A Wani

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5 November 2019

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1 March 2000

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5 November 2019

Mutation Research

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5 November 2019

459

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5 November 2019

135-145

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5 November 2019

2

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5 November 2019

Role of DNA excision repair gene defects in the etiology of cancer.

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Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients

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DNA excision repair

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Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts

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Reduced DNA repair synthesis in healthy women having first degree relatives with breast cancer

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DNA lesions, inducible DNA repair, and cell division: three key factors in mutagenesis and carcinogenesis

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Somatic mutation theory, DNA repair rates, and the molecular epidemiology of p53 mutations

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Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

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Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

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p53 modulation of TFIIH-associated nucleotide excision repair activity

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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Influence of p53 tumor suppressor protein on bias of DNA repair and apoptotic response in human cells

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Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

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Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene

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Role of DNA repair in malignant neoplastic transformation of human mammary epithelial cells in culture

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Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types

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Modulation of (+/-)-anti-BPDE mediated p53 accumulation by inhibitors of protein kinase C and poly(ADP-ribose) polymerase

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Rapid activation of apoptosis in human promyelocytic leukemic cells by (+/-)-anti-benzo[a]pyrene diol epoxide induced DNA damage

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DNA repair in human cells: quantitative assessment of bulky anti-BPDE-DNA adducts by non-competitive immunoassays.

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7 January 2021

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Quantitation of pyrimidine dimers by immunoslot blot following sublethal UV-irradiation of human cells

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7 January 2021

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Antibodies to UV irradiated DNA: the monitoring of DNA damage by ELISA and indirect immunofluorescence

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Using UvrABC nuclease to detect 7,12-dimethylbenz[a]anthracene anti-diol epoxide-DNA binding specificity in the mouse H-ras gene.

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Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts

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Efficient synthesis of 32P-labeled single-stranded DNA probes using linear PCR; application of the method for analysis of strand-specific DNA repair

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Assessment of DNA damage and repair in specific genomic regions by quantitative immuno-coupled PCR.

1 reference

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7 January 2021

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Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.

1 reference

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p53 status and the efficacy of cancer therapy in vivo

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Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

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A p53-dependent mouse spindle checkpoint

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Evidence for a p53-independent pathway for upregulation of SDI1/CIP1/WAF1/p21 RNA in human cells

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Potential roles for p53 in nucleotide excision repair.

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Aberrant p21WAF1-dependent growth arrest as the possible mechanism of abnormal resistance to ultraviolet light cytotoxicity in Li-Fraumeni syndrome fibroblast strains heterozygous for TP53 mutations.

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The human papilloma virus 16E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage

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Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis

1 reference

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UV radiation is a transcriptional inducer of p21(Cip1/Waf1) cyclin-kinase inhibitor in a p53-independent manner

1 reference

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Identifiers

10.1016/S0921-8777(99)00066-X

1 reference

Europe PubMed Central

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5 November 2019

1 reference

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5 November 2019

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