(Q73573749)

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Structural determinants for the activation mechanism of the angiotensin II type 1 receptor differ for phosphoinositide hydrolysis and mitogen-activated protein kinase pathways

scientific article published on 01 July 2003

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5 November 2019

Structural determinants for the activation mechanism of the angiotensin II type 1 receptor differ for phosphoinositide hydrolysis and mitogen-activated protein kinase pathways (English)

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5 November 2019

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John Hines

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5 November 2019

Steven J Fluharty

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5 November 2019

Daniel K Yee

3

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1 July 2003

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5 November 2019

Biochemical Pharmacology

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5 November 2019

66

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5 November 2019

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5 November 2019

251-262

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5 November 2019

Angiotensin, thirst, and sodium appetite.

1 reference

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Angiotensin II signaling in vascular smooth muscle. New concepts

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Central role of the MAPK pathway in ang II-mediated DNA synthesis and migration in rat vascular smooth muscle cells.

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Role of Janus kinase/signal transducer and activator of transcription and mitogen-activated protein kinase cascades in angiotensin II- and platelet-derived growth factor-induced vascular smooth muscle cell proliferation.

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7 January 2021

Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor.

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Angiotensin and its AT2 receptor: new insights into an old system

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Expression of AT2 receptors in the developing rat fetus

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7 January 2021

Angiotensin II type 2 receptor mediates programmed cell death

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Angiotensin II receptor subtypes: characterization, signalling mechanisms, and possible physiological implications.

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7 January 2021

The role of angiotensin receptors in cardiovascular diseases

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Angiotensin II receptor subtypes and phosphoinositide hydrolysis in rat adrenal medulla.

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7 January 2021

Control of glomerulosa cell function by angiotensin II: transduction by G-proteins and inositol polyphosphates

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Novel nuclear signaling pathway mediates activation of fibroblast growth factor-2 gene by type 1 and type 2 angiotensin II receptors

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7 January 2021

MAP Kinase in the rat adrenal gland

1 reference

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7 January 2021

Mitogen-activated protein kinases in rat brain neuronal cultures are activated by angiotensin II type 1 receptors and inhibited by angiotensin II type 2 receptors

1 reference

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7 January 2021

Angiotensin II responses of vascular smooth muscle cells from hypertensive rats: enhancement at the level of p42 and p44 mitogen activated protein kinase.

1 reference

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7 January 2021

Differentiation between binding sites for angiotensin II and nonpeptide antagonists on the angiotensin II type 1 receptors

1 reference

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7 January 2021

Functional domains of the C-terminus of the rat angiotensin AT1A receptor

1 reference

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7 January 2021

A Conserved NPLFY Sequence Contributes to Agonist Binding and Signal Transduction but Is Not an Internalization Signal for the Type 1 Angiotensin II Receptor

1 reference

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7 January 2021

Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C

1 reference

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7 January 2021

Mutation of Asp74 of the rat angiotensin II receptor confers changes in antagonist affinities and abolishes G-protein coupling.

1 reference

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7 January 2021

Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations

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7 January 2021

Chimeric AT1/AT2 receptors reveal functional similarities despite key amino acid dissimilarities in the domains mediating agonist-dependent activation

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7 January 2021

Angiotensin II-induced down-regulation of inositol trisphosphate receptors in WB rat liver epithelial cells. Evidence for involvement of the proteasome pathway

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7 January 2021

Cloning and expression of angiotensin II type 2 (AT2) receptors from murine neuroblastoma N1E-115 cells: evidence for AT2 receptor heterogeneity.

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7 January 2021

Synthesis and structure-activity relationships of a novel series of non-peptide angiotensin II receptor binding inhibitors specific for the AT2 subtype

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7 January 2021

A computer modeling postulated mechanism for angiotensin II receptor activation

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7 January 2021

A review of mutagenesis studies of angiotensin II type 1 receptor, the three-dimensional receptor model in search of the agonist and antagonist binding site and the hypothesis of a receptor activation mechanism

1 reference

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7 January 2021

The third cytoplasmic loop of the angiotensin II type 1 receptor exerts differential effects on extracellular signal-regulated kinase (ERK1/ERK2) and apoptosis via Ras- and Rap1-dependent pathways

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7 January 2021

Domains for G-protein coupling in angiotensin II receptor type I: studies by site-directed mutagenesis

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7 January 2021

Identification of a domain in the angiotensin II type 1 receptor determining Gq coupling by the use of receptor chimeras

1 reference

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7 January 2021

Mapping of G protein coupling sites of the angiotensin II type 1 receptor

1 reference

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7 January 2021

Tyrosine kinase activation by the angiotensin II receptor in the absence of calcium signaling

1 reference

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7 January 2021

AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs.

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7 January 2021

Identifiers

10.1016/S0006-2952(03)00257-0

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12826267%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12826267%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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