Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q73574910)
Watch
English
V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation
scientific article published on 01 July 1997
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
title
V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
author name string
M A Bogue
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
C Wang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
C Zhu
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
D B Roth
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
publication date
1 July 1997
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
published in
Immunity
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
7
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
37-47
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
cites work
Normal D-JH rearranged products of the IgH gene in SCID mouse bone marrow.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biased T-cell receptor delta element recombination in scid thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enumeration and characterization of DJH structures in mouse fetal liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell receptor delta gene rearrangements in early thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initiation of V(D)J recombination in vitro obeying the 12/23 rule
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of the V(D)J recombination mechanism on the formation of the primary T and B cell repertoires
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal deletions in the T-cell receptor delta locus of mouse thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extent to which homology can constrain coding exon junctional diversity in V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence-specific DNA binding by Ku autoantigen and its effects on transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking TdT: mature animals with an immature lymphocyte repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking terminal deoxynucleotidyl transferase: adult mice with a fetal antigen receptor repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell receptor gamma and delta gene junctional sequences in SCID mice: excessive P nucleotide insertion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel strand exchanges in V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P nucleotides in V(D)J recombination: a fine-structure analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The V(D)J recombination defect in the xrs-6 cell line results from a point mutation in the Ku80 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the mechanism of interaction of simian Ku protein with DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High frequency of normal DJH joints in B cell progenitors in severe combined immunodeficiency mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A DNA end-binding factor involved in double-strand break repair and V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of nonhomologous recombination in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of filler DNA at immune, nonimmune, and oncogenic rearrangements suggests multiple mechanisms of formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of broken DNA molecules associated with V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repair and recombination. How to make ends meet
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coding joint formation of endogenous T cell receptor genes in lymphoid cells from scid mice: unusual P-nucleotide additions in VJ-coding joints
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inversions produced during V(D)J rearrangement at IgH, the immunoglobulin heavy-chain locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impairment of V(D)J recombination in double-strand break repair mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Similarities between initiation of V(D)J recombination and retroviral integration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initiation of V(D)J recombination in a cell-free system.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of short homology repeats and TdT in generation of the invariant gamma delta antigen receptor repertoire in the fetal thymus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of coding ends in thymocytes of scid mice: implications for the mechanism of V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980508-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(00)80508-7
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed ID
9252118
1 reference
stated in
Europe PubMed Central
PubMed ID
9252118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit