(Q73575683)

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Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl

scientific article published on 01 March 2000

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5 November 2019

Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl (English)

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5 November 2019

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5 November 2019

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Fusi F

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5 November 2019

Frosini M

3

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5 November 2019

Pessina F

4

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5 November 2019

Tipton KF

5

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5 November 2019

Sgaragli GP

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5 November 2019

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1 March 2000

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5 November 2019

European Journal of Pharmacology

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5 November 2019

391

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5 November 2019

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5 November 2019

199-206

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5 November 2019

Metabolism of monoamine oxidase inhibitors

1 reference

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7 January 2021

Investigation by Parkinson's Disease Research Group of United Kingdom into excess mortality seen with combined levodopa and selegiline treatment in patients with early, mild Parkinson's disease: further results of randomised trial and confidential i

1 reference

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7 January 2021

Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study

1 reference

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Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats

1 reference

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7 January 2021

Hormonal regulation of microsomal cytochrome P4502E1 and P450 reductase in rat liver and kidney

1 reference

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7 January 2021

Inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole in vitro. Increased effectiveness after induction by pyrazole and 4-methylpyrazole

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7 January 2021

Pharmacology of selegiline

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7 January 2021

Atypical metabolism of deprenyl and its enantiomer, (S)-(+)-N,alpha-dimethyl-N-propynylphenethylamine, by cytochrome P450 2D6.

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7 January 2021

Safety of selegiline (deprenyl) in the treatment of Parkinson's disease

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7 January 2021

Comparison of therapeutic effects and mortality data of levodopa and levodopa combined with selegiline in patients with early, mild Parkinson's disease. Parkinson's Disease Research Group of the United Kingdom

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7 January 2021

L-(-)-desmethylselegiline, a metabolite of selegiline [L-(-)-deprenyl], protects mesencephalic dopamine neurons from excitotoxicity in vitro.

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7 January 2021

Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse.

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7 January 2021

Etiology and pathogenesis of Parkinson's disease

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7 January 2021

Spectral and kinetic studies of the interaction of imidazole anti-fungal agents with microsomal cytochromes P-450

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7 January 2021

CYP2D6 polymorphism is not crucial for the disposition of selegiline*

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7 January 2021

Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration

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7 January 2021

Rescue of dying neurons: A new action for deprenyl in MPTP parkinsonism

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7 January 2021

The effect of deprenyl (selegiline) on the natural history of Parkinson's disease

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7 January 2021

Effect of deprenyl on the progression of disability in early Parkinson's disease

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7 January 2021

Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease

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7 January 2021

What is it that l-deprenyl (selegiline) might do?

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7 January 2021

Hepatic and extrahepatic metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor, of amphetamines in rats: sex and strain differences.

1 reference

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7 January 2021

Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: relationship of metabolism to MAO-B inhibitory potency

1 reference

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7 January 2021

Identifiers

10.1016/S0014-2999(00)00078-9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729359%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729359%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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