(Q73585255)

English

Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) on N-formyl-methionyl-leucyl-phenylalanine-induced phospholipase D activation in differentiated HL60 cells: possible involvement of phosphatidylinositol 3-kinase in

scientific article published on 01 June 1997

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scholarly article

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5 November 2019

Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) on N-formyl-methionyl-leucyl-phenylalanine-induced phospholipase D activation in differentiated HL60 cells: possible involvement of phosphatidylinositol 3-kinase in phospholipase D activation (English)

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5 November 2019

Mitsuhiro Nakamura

1

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5 November 2019

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S Nakashima

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5 November 2019

Y Katagiri

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5 November 2019

Y Nozawa

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1 June 1997

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5 November 2019

Biochemical Pharmacology

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5 November 2019

53

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5 November 2019

1929-1936

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5 November 2019

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5 November 2019

Protein kinase C and lipid signaling for sustained cellular responses

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Inositol phosphates and cell signalling

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Phosphatidylcholine breakdown and signal transduction

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The regulation and cellular functions of phosphatidylcholine hydrolysis

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Correlation between secretion and phospholipase D activation in differentiated HL60 cells.

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Phospholipase D activation is functionally linked to superoxide generation in the human neutrophil

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Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

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Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

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Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation

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Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

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7 January 2021

Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils

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Activation of membrane-bound phospholipase D by protein kinase C in HL60 cells: synergistic action of a small GTP-binding protein RhoA.

1 reference

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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7 January 2021

Stimulation of phosphatidic acid production in platelets precedes the formation of arachidonate and parallels the release of serotonin

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Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

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Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

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Association between leukotriene B4-induced phospholipase D activation and degranulation of human neutrophils

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Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells

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Antiinflammatory activity of the new mould metabolite 11-desacetoxy-wortmannin and of some of its derivatives

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7 January 2021

The phosphatidylinositol 3-kinase inhibitor, wortmannin, inhibits insulin-induced activation of phosphatidylcholine hydrolysis and associated protein kinase C translocation in rat adipocytes

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7 January 2021

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

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7 January 2021

Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

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A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

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Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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7 January 2021

Ras mediates the activation of phospholipase D by v-Src

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7 January 2021

Regulation of phospholipase D in HL60 cells. Evidence for a cytosolic phospholipase D.

1 reference

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7 January 2021

Resolved phospholipase D activity is modulated by cytosolic factors other than Arf

1 reference

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7 January 2021

Regulation of membrane-bound phospholipase D by protein kinase C in HL60 cells. Synergistic action of small GTP-binding protein RhoA.

1 reference

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7 January 2021

Activation of human neutrophil phospholipase D by three separable mechanisms

1 reference

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7 January 2021

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10.1016/S0006-2952(97)00169-X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9256168%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9256168%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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