(Q73615689)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12842621%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Downregulation of CD4 is required for maintenance of viral infectivity of HIV-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12842621%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

Masakazu Tanaka

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12842621%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Takaharu Ueno

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12842621%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Tomomi Nakahara

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12842621%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Kenta Sasaki

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12842621%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Akinori Ishimoto

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12842621%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Hiroyuki Sakai

6

1 reference

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5 November 2019

publication date

1 July 2003

1 reference

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5 November 2019

volume

311

1 reference

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5 November 2019

issue

2

1 reference

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5 November 2019

page(s)

316-325

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12842621%20AND%20SRC:MED&resulttype=core&format=json

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

5 November 2019

cites work

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Generation and characterization of the human immunodeficiency virus type 1 mutants

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7 January 2021

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

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7 January 2021

Human immunodeficiency virus type 1 Vpr protein does not modulate surface expression of the CD4 receptor

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7 January 2021

Cell surface CD4 inhibits HIV-1 particle release by interfering with Vpu activity.

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7 January 2021

Impairment of human immunodeficiency virus type 1 (HIV-1) entry into Jurkat T cells by constitutive expression of the HIV-1 vpr protein: role of CD4 down-modulation

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7 January 2021

Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells

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7 January 2021

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

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7 January 2021

A soluble form of CD4 (T4) protein inhibits AIDS virus infection

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7 January 2021

Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes

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7 January 2021

Characterization of a continuous T-cell line susceptible to the cytopathic effects of the acquired immunodeficiency syndrome (AIDS)-associated retrovirus

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7 January 2021

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

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7 January 2021

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

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7 January 2021

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

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7 January 2021

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

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7 January 2021

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

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7 January 2021

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

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7 January 2021

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

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7 January 2021

Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner

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7 January 2021

Human immunodeficiency virus (HIV) type 1 can superinfect HIV-2-infected cells: pseudotype virions produced with expanded cellular host range

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7 January 2021

Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes

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7 January 2021

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

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7 January 2021

The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane

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7 January 2021

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

1 reference

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7 January 2021

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

1 reference

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7 January 2021

Mechanisms of human papillomavirus E2-mediated repression of viral oncogene expression and cervical cancer cell growth inhibition

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7 January 2021

Functional association between the nef gene product and gag-pol region of HIV-1.

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7 January 2021

Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells

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7 January 2021

Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes

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7 January 2021

The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors

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7 January 2021

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

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7 January 2021

The dileucine-based sorting motif in HIV-1 Nef is not required for down-regulation of class I MHC.

1 reference

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7 January 2021

Recombination in AIDS viruses

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7 January 2021

Recombination in HIV-1

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7 January 2021

Accumulation of human immunodeficiency virus type 1 DNA in T cells: results of multiple infection events.

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7 January 2021

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

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7 January 2021

Function of human immunodeficiency virus type 1 Vpu protein in various cell types.

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7 January 2021

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

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7 January 2021

Unexpectedly high levels of HIV-1 RNA and protein synthesis in a cytocidal infection.

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7 January 2021

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

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7 January 2021

The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. I. Establishment of interference

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7 January 2021

Envelope glycoprotein of HIV induces interference and cytolysis resistance in CD4+ cells: mechanism for persistence in AIDS.

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7 January 2021

A novel gene of HIV-1, vpu, and its 16-kilodalton product

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7 January 2021

Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1

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7 January 2021

Enhancement of human immunodeficiency virus type 1 infectivity by Nef is producer cell-dependent.

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7 January 2021

Preparation and characterization of human HIV type 1 neutralizing reference sera

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7 January 2021

Signal transduction by lymphocyte antigen receptors

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7 January 2021

Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis

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7 January 2021

Dissociation of unintegrated viral DNA accumulation from single-cell lysis induced by human immunodeficiency virus type 1.

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7 January 2021

The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900126-0

7 January 2021

Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900126-0

7 January 2021

Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900126-0

7 January 2021

Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry.

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900126-0

7 January 2021

CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2803%2900126-0

7 January 2021

Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs

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7 January 2021

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo

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7 January 2021

Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein

1 reference

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7 January 2021

10.1016/S0042-6822(03)00126-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12842621%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference