(Q73665645)

English

CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents

scientific article published on 01 April 2000

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scholarly article

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5 November 2019

CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10760358%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Frank S. Menniti

1

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5 November 2019

author name string

M J Pagnozzi

2

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5 November 2019

P Butler

3

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5 November 2019

B L Chenard

4

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5 November 2019

S S Jaw-Tsai

5

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5 November 2019

W Frost White

6

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5 November 2019

publication date

1 April 2000

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5 November 2019

Neuropharmacology

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5 November 2019

39

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5 November 2019

7

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5 November 2019

1147-1155

1 reference

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5 November 2019

Induction of spreading depression in the ischemic hemisphere following experimental middle cerebral artery occlusion: effect on infarct morphology.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Convulsant agents activate c-fos induction in both a calmodulin-dependent and calmodulin-independent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

NMDA receptor-dependent and -independent immediate early gene expression induced by focal mechanical brain injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Functional consequences of NR2 subunit composition in single recombinant N-methyl-D-aspartate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

(1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: a potent new neuroprotectant which blocks N-methyl-D-aspartate responses

1 reference

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7 January 2021

Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists

2 references

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Impairment of Fos protein formation in the rat infarct borderzone by MK-801, but not by NBQX.

2 references

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of CP101,606, a novel NR2B subunit antagonist of the N-methyl-D-aspartate receptor, on the volume of ischemic brain damage off cytotoxic brain edema after middle cerebral artery occlusion in the feline brain

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Reserpine potentiates NMDA-induced c-fos mRNA expression in the mouse brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischaemia in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Ketamine blockade of cortical spreading depression in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Excitatory amino acid-induced cytotoxicity in primary cultures of mouse cerebellar granule cells correlates with elevated, sustained c-fos protoncogene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Association of c-fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

JUN, FOS, KROX, and CREB transcription factor proteins in the rat cortex: basal expression and induction by spreading depression and epileptic seizures.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Spreading depression induces c-fos-like immunoreactivity and NGF mRNA in the rat cerebral cortex.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: effect on volume of ischemic injury

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Homolateral cerebrocortical increase of immediate early gene and neurotransmitter messenger RNAs after minimal cortical lesion: blockade by N-methyl-D-aspartate antagonist.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

MK-801 inhibits the induction of immediate early genes in cerebral cortex, thalamus, and hippocampus, but not in substantia nigra following middle cerebral artery occlusion

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Molecular diversity of the NMDA receptor channel

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

CP-101,606, a potent neuroprotectant selective for forebrain neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Sustained c-fos expression is associated with excitotoxicity during the development of neuronal cells in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Structure and function of the NMDA receptor channel

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Inhibition of cortical spreading depression by L-701,324, a novel antagonist at the glycine site of the N-methyl-D-aspartate receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Effects of the NMDA antagonist CP-98,113 on regional cerebral edema and cardiovascular, cognitive, and neurobehavioral function following experimental brain injury in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Effects of the novel NMDA antagonists CP-98,113, CP-101,581 and CP-101,606 on cognitive function and regional cerebral edema following experimental brain injury in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

NMDA receptor overstimulation triggers a prolonged wave of immediate early gene expression: relationship to excitotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Binding of [3H]ifenprodil, a novel NMDA antagonist, to a polyamine-sensitive site in the rat cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

The role of spreading depression in focal ischemia evaluated by diffusion mapping

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

The neuroprotective effect of the forebrain-selective NMDA antagonist CP101,606 upon focal ischemic brain damage caused by acute subdural hematoma in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Mechanisms involved in spreading depression.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Anticonvulsant agents, dizocilpine maleate, enadoline and HA 966 have different effects on N-methyl-DL-aspartate-induced immediate early gene induction in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900211-7

7 January 2021

Identifiers

10.1016/S0028-3908(99)00211-7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10760358%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10760358%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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