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6-Alkylandrosta-4,6-diene-3,17-diones and their 1,4,6-triene analogs as aromatase inhibitors. Structure-activity relationships
scientific article published on 01 August 1997
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
title
6-Alkylandrosta-4,6-diene-3,17-diones and their 1,4,6-triene analogs as aromatase inhibitors. Structure-activity relationships
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author name string
M Numazawa
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
M Oshibe
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
S Yamaguchi
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
publication date
1 August 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Steroids
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
62
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
8-9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
595-602
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
cites work
Purification of human placental aromatase cytochrome P-450 with monoclonal antibody and its characterization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conversion of 19-hydroxy-delta 4-androstene-3,17-dione to estrone by endocrine tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanistic studies on C-19 demethylation in oestrogen biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissociation of 19-hydroxy- 19-oxo-, and aromatizing-activities in human placental microsomes through the use of suicide substrates to aromatase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on the mechanism of estrogen biosynthesis. 3. The stereochemistry of aromatization of C19 and C18 steroids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conversion of 19-oxo[2 beta-2H]androgens into oestrogens by human placental aromatase. An unexpected stereochemical outcome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Effect of an Aromatase Inhibitor, 4-Hydroxy-4-Androstene- 3,17-Dione, On Estrogen-Dependent Processes in Reproduction and Breast Cancer11
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aromatase inhibitors: their biochemistry and clinical potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of P450-dependent steroid biosynthesis: from research to medical treatment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aromatase and its inhibitors in breast cancer treatment--overview and perspective
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on the mechanism of estrogen biosynthesis. 8. The development of inhibitors of the enzyme system in human placenta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enzyme-generated intermediates derived from 4-androstene-3,6,17-trione and 1,4,6-androstatriene-3,17-dione cause a time-dependent decrease in human placental aromatase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of an aromatase inhibitor, 1,4,6-androstatriene-3,17-dione, on 7,12-dimethylbenz[a]anthracene-induced mammary tumors in the rat and its mechanism of action in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
7-substituted 1,4,6-androstatriene-3,17-diones as enzyme-activated irreversible inhibitors of aromatase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aromatase inhibitors. Synthesis and biological activity of androstenedione derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-Aminoandrostenedione derivatives: a novel class of irreversible aromatase inhibitors. Comparison with FCE 24304 and 4-hydroxyandrostenedione
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and aromatase inhibition by potential metabolites of exemestane (6-methylenandrosta-1,4-diene-3,17-dione)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and biochemical studies of 7-substituted 4,6-androstadiene-3,17-diones as aromatase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
6-Alkyl- and 6-arylandrost-4-ene-3,17-diones as aromatase inhibitors. Synthesis and structure-activity relationships
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Further studies on 6-alkylandrost-4-ene-3,17-diones as aromatase inhibitors: elongation of the 6-alkyl chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Time-dependent inactivation of aromatase by 6-alkylandrosta-1,4-diene-3,17-diones. Effects of length and configuration of 6-alkyl group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies of human placental aromatase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and biochemical studies of 16- or 19-substituted androst-4-enes as aromatase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0039-128X%2897%2986814-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0039-128X(97)86814-6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed publication ID
9292934
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9292934
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9292934%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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