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Defective cleavage of membrane bound TGFalpha leads to enhanced activation of the EGF receptor in malignant cells
scientific article published on 01 April 2000
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
title
Defective cleavage of membrane bound TGFalpha leads to enhanced activation of the EGF receptor in malignant cells
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author
Dianhua Jiang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Jiurong Liang
series ordinal
4
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Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author name string
Yang H
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Li W
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3
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Europe PubMed Central
PubMed publication ID
10773880
reference URL
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retrieved
6 November 2019
Gentry LE
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Brattain MG
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
language of work or name
English
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publication date
1 April 2000
1 reference
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Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Oncogene
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Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
19
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Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
15
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Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
1901-1914
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Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1203513
0 references
cites work
Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors.
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Autocrine regulation of membrane transforming growth factor-alpha cleavage
1 reference
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Crossref
reference URL
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7 January 2021
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Expression of the transforming growth factor-alpha/epidermal growth factor receptor pathway in normal human breast epithelial cells
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGF alpha into soluble growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transmembrane TGF-alpha precursors activate EGF/TGF-alpha receptors.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterogeneity of human colon carcinoma
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Different transforming growth factor-alpha species are derived from a glycosylated and palmitoylated transmembrane precursor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human transforming growth factor-alpha: precursor structure and expression in E. coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and characterization of transforming growth factor alpha precursor protein in transfected mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
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7 January 2021
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inferred from DOI database lookup
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
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7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant regulation of transforming growth factor-alpha during the establishment of growth arrest and quiescence of growth factor independent cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of transforming growth factor alpha expression in a growth factor-independent cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autocrine transforming growth factor alpha provides a growth advantage to malignant cells by facilitating re-entry into the cell cycle from suboptimal growth states.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EGF receptor in neoplasia and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and sequence analysis of a cDNA for rat transforming growth factor-alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of larger polypeptides structurally and functionally related to type I transforming growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of high molecular weight transforming growth factor alpha produced by rat hepatocellular carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane-anchored growth factors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
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inferred from DOI database lookup
Consumption of EGF by A431 cells: evidence for receptor recycling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane-anchored heparin-binding epidermal growth factor-like growth factor acts as a tumor survival factor in a hepatoma cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-alpha expression in the anterior pituitary gland: regulation by epidermal growth factor and phorbol ester in dispersed cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
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7 January 2021
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inferred from DOI database lookup
ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of the membrane precursor for transforming growth factor alpha is a regulated process
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A thousand and two protein tyrosine phosphatases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preparation and binding of radioactively labeled porcine transforming growth factor type beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein-tyrosine phosphatase-mediated decrease of epidermal growth factor and platelet-derived growth factor receptor tyrosine phosphorylation in high cell density cultures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endocytosis of growth factor receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autocrine secretion and malignant transformation of cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203513
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1203513
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Dimensions Publication ID
1006308897
0 references
PubMed publication ID
10773880
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10773880
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773880%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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