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Why "underpowered" trials are not necessarily unethical
scientific article published on 01 September 1997
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
title
Why "underpowered" trials are not necessarily unethical
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author name string
S J Edwards
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
R J Lilford
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
D Braunholtz
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
J Jackson
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
language of work or name
English
0 references
publication date
1 September 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
The Lancet
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
350
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
9080
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
804-807
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
cites work
Statistics and ethics in medical research: III How large a sample?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sample size: how many patients are necessary?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Must clinical trials be large? The interpretation of P-values and the combination of test results
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Size of trials for evaluation of antenatal tests of fetal wellbeing in high risk pregnancy
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
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7 January 2021
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The statistical basis of public policy: a paradigm shift is overdue
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Crossref
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7 January 2021
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"Meta-analysis: statistical alchemy for the 21st century": discussion. A plea for a more balanced view of meta-analysis and systematic overviews of the effect of health care interventions.
1 reference
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Crossref
reference URL
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7 January 2021
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Can meta-analyses be trusted?
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
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Growing pains of meta-analysis
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Crossref
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https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Large trials vs meta-analysis of smaller trials: how do their results compare?
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Incorporating variations in the quality of individual randomized trials into meta-analysis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
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7 January 2021
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Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials
1 reference
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Crossref
reference URL
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7 January 2021
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A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction
1 reference
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Crossref
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7 January 2021
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Towards an international register of cancer trials: the UKCCCR register of U.K. trials.
1 reference
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Crossref
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7 January 2021
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Meta-analysis of the literature or of individual patient data: is there a difference?
1 reference
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Crossref
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7 January 2021
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The alpha and beta errors in randomized trials
1 reference
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Crossref
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7 January 2021
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Explanatory and pragmatic attitudes in therapeutical trials
1 reference
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Crossref
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7 January 2021
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Evaluating new treatments and diagnostic technologies in obstetrics. Practical problems, ethics, and solutions
1 reference
stated in
Crossref
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7 January 2021
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The size of clinical trials in cancer research--what are the current needs? Medical Research Council Cancer Therapy Committee
1 reference
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Crossref
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7 January 2021
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Clinical trials and rare diseases: a way out of a conundrum
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
The use of predicted confidence intervals when planning experiments and the misuse of power when interpreting results.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of p-values in analysing trial results
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ethically optimised designs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2897%2902290-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0140-6736(97)02290-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed publication ID
9298015
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9298015
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9298015%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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