(Q73711189)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11286938%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

A "two-hit" model of cystogenesis in autosomal dominant polycystic kidney disease? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11286938%20AND%20SRC:MED&resulttype=core&format=json

autosomal dominant polycystic kidney disease

6 November 2019

main subject

1 reference

autosomal dominant polycystic kidney

inferred from title

1 reference

Y Pei

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11286938%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

publication date

1 April 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11286938%20AND%20SRC:MED&resulttype=core&format=json

Trends in Molecular Medicine

6 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11286938%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11286938%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11286938%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

151-156

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11286938%20AND%20SRC:MED&resulttype=core&format=json

Polycystic kidney disease: Clues to pathogenesis

6 November 2019

cites work

1 reference

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7 January 2021

The diagnosis and prognosis of autosomal dominant polycystic kidney disease

1 reference

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7 January 2021

Autosomal dominant polycystic kidney disease: clues to pathogenesis

1 reference

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7 January 2021

Autosomal dominant polycystic kidney disease: molecular genetics and molecular pathogenesis.

1 reference

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7 January 2021

Molecular genetics and mechanism of autosomal dominant polycystic kidney disease

1 reference

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7 January 2021

The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

PKD1 interacts with PKD2 through a probable coiled-coil domain

1 reference

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7 January 2021

Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

1 reference

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7 January 2021

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

1 reference

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7 January 2021

Apoptosis and loss of renal tissue in polycystic kidney diseases

1 reference

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7 January 2021

Intrafamilial phenotypic expression of autosomal dominant polycystic kidney disease

1 reference

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7 January 2021

A stable, nonsense mutation associated with a case of infantile onset polycystic kidney disease 1 (PKD1).

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Multilocus polycystic disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.

1 reference

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7 January 2021

Loss of the polycystic kidney disease (PKD1) region of chromosome 16p13 in renal cyst cells supports a loss-of-function model for cyst pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Loss of heterozygosity in polycystic kidney disease with a missense mutation in the repeated region of PKD1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Loss of heterozygosity in renal and hepatic epithelial cystic cells from ADPKD1 patients

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Somatic mutation in individual liver cysts supports a two-hit model of cystogenesis in autosomal dominant polycystic kidney disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

1 reference

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7 January 2021

Late onset of renal and hepatic cysts in Pkd1-targeted heterozygotes

1 reference

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7 January 2021

Polycystin 1 is required for the structural integrity of blood vessels

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Somatic inactivation of Pkd2 results in polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

A loss-of-function model for cystogenesis in human autosomal dominant polycystic kidney disease type 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Germinal and somatic mutations in the PKD2 gene of renal cysts in autosomal dominant polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Genetic evidence for a trans-heterozygous model for cystogenesis in autosomal dominant polycystic kidney disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Molecular basis of renal cyst formation--one hit or two?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Identification and localization of polycystin, the PKD1 gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Coordinate expression of the autosomal dominant polycystic kidney disease proteins, polycystin-2 and polycystin-1, in normal and cystic tissue.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Polycystin-1 expression in PKD1, early-onset PKD1, and TSC2/PKD1 cystic tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Seven novel mutations of the PKD2 gene in families with autosomal dominant polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Somatic mutations are frequent and increase with age in human kidney epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Estimation of mutation frequencies in normal mammalian cells and the development of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

DNA repair: a double-edged sword

1 reference

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7 January 2021

Environment and cancer: who are susceptible?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2901953-0

7 January 2021

Genetic identification of two major modifier loci of polycystic kidney disease progression in pcy mice

1 reference

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7 January 2021

Molecular mechanisms of genetic polymorphisms of drug metabolism

1 reference

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7 January 2021

10.1016/S1471-4914(01)01953-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11286938%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference