(Q73740016)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Histidine to alanine mutants of human dihydroorotate dehydrogenase. Identification of a brequinar-resistant mutant enzyme (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

J P Davis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

R A Copeland

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

language of work or name

English

0 references

publication date

1 August 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

published in

Biochemical Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

459-465

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

The development of Brequinar as an immunosuppressive drug for transplantation

6 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

Leflunomide (HWA 486), a novel immunomodulating compound for the treatment of autoimmune disorders and reactions leading to transplantation rejection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

Dihydroorotate dehydrogenase is a high affinity binding protein for A77 1726 and mediator of a range of biological effects of the immunomodulatory compound

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

Recombinant human dihydroorotate dehydrogenase: expression, purification, and characterization of a catalytically functional truncated enzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

Cloning and sequencing of a human cDNA coding for dihydroorotate dehydrogenase by complementation of the corresponding yeast mutant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

9 Dihydroorotate dehydrogenase (Neurospora)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

17 The kinetics of reversible tight-binding inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

Structure-activity relationship of quinoline carboxylic acids. A new class of inhibitors of dihydroorotate dehydrogenase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900197-4

10.1016/S0006-2952(97)00197-4

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9313772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference