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The genetics of Alzheimer's disease
scientific article published on 01 August 1997
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
The genetics of Alzheimer's disease
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
main subject
Alzheimer's disease
1 reference
based on heuristic
inferred from title
author name string
D C Rubinsztein
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
publication date
1 August 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Progress in Neurobiology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
52
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
447-454
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
cites work
APOE genotype influences functional status among elderly without dementia.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
ApoE genotype and survival from intracerebral haemorrhage
1 reference
stated in
Crossref
reference URL
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7 January 2021
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The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 5-repeat allele in the very-low-density lipoprotein receptor gene polymorphism is not increased in sporadic Alzheimer's disease in Japanese.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevalence of dementia and distribution of ApoE alleles in Japanese centenarians: an almost-complete survey in Yamanashi Prefecture, Japan
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protective effect of apoE epsilon 2 in Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
No increased risk of the apolipoprotein E epsilon2 allele with early-onset Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The apolipoprotein E epsilon 4 allele does not influence the clinical expression of the amyloid precursor protein gene codon 693 or 692 mutations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No genetic effect of alpha1-antichymotrypsin in Alzheimer disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Arginine residues at codons 112 and 158 in the apolipoprotein E gene correspond to the ancestral state in humans.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular genetics of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ApoE genotype and Down's syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuropathological changes in Down's syndrome hippocampal formation. Effect of age and apolipoprotein E genotype.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein-E genotyping in diagnosis of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E and Alzheimer's disease: ethnic variation in genotypic risks.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E: cholesterol transport protein with expanding role in cell biology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The extent of amyloid deposition in brain in patients with Down's syndrome does not depend upon the apolipoprotein E genotype.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Untangling the pathophysio-chemistry of β-amyloid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid beta-protein, APOE genotype and head injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of an association between apolipoprotein E epsilon 4 and Alzheimer's disease in elderly Nigerians
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease and apolipoprotein E-4 allele in an Amish population.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta APP mRNA transcription is increased in cultured fibroblasts from the familial Alzheimer's disease-1 family.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease in Finnish twins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The future of genetic studies of complex human diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Alzheimer diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E epsilon 2 allele promotes longevity and protects patients with Down's syndrome from dementia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E: a review of its roles in lipoprotein metabolism, neuronal growth and repair and as a risk factor for Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apo E genotypes in multiple sclerosis, Parkinson's disease, schwannomas and late-onset Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease and possible gene interaction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Onset of dementia is associated with apolipoprotein E epsilon4 in Down's syndrome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presenilin-1 polymorphism and Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein-E genotyping in diagnosis of Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of association of apolipoprotein E allele epsilon 4 with late-onset Alzheimer's disease among Finnish centenarians
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E, memory and Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epistatic effect of APP717 mutation and apolipoprotein E genotype in familial Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protection against Alzheimer's disease with apoE epsilon 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E genotype does not affect age at onset in patients with chromosome 14 encoded Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tRNA(Gln) 4336 mitochondrial DNA variant is not a high penetrance mutation which predisposes to dementia before the age of 75 years.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of alpha-1 antichymotrypsin, presenilin-1, angiotensin-converting enzyme, and methylenetetrahydrofolate reductase loci as candidates for dementia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presenilin-1 intron 8 polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
APOE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presenilins and Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The apolipoprotein E epsilon 2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A case-control study of apolipoprotein E genotypes in Alzheimer's disease associated with Down's syndrome. Dutch Study Group on Down's Syndrome and Ageing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency of the apolipoprotein E epsilon 2 allele is diminished in sporadic Alzheimer disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The influence of apolipoprotein E isotypes on Alzheimer's disease pathology in 40 cases of Down's syndrome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No association found between Alzheimer's disease and a mitochondrial tRNA glutamine gene variant.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease. Alzheimer's Disease Collaborative Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900014-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0301-0082(97)00014-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed publication ID
9316155
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9316155
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9316155%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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