(Q73794585)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

1 reference

K S Lown

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

R R Mayo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

A B Leichtman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

H L Hsiao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

D K Turgeon

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

P Schmiedlin-Ren

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

M B Brown

7

1 reference

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6 November 2019

W Guo

8

1 reference

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6 November 2019

S J Rossi

9

1 reference

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6 November 2019

L Z Benet

10

1 reference

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6 November 2019

P B Watkins

11

1 reference

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6 November 2019

publication date

1 September 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

6 November 2019

published in

1 reference

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6 November 2019

volume

62

1 reference

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6 November 2019

issue

3

1 reference

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6 November 2019

page(s)

248-260

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

Intraindividual variability in the relative systemic availability of cyclosporin after oral dosing

6 November 2019

cites work

1 reference

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7 January 2021

1 reference

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Cyclosporine metabolism in human liver: identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Purification of a human liver cytochrome P-450 immunochemically related to several cytochromes P-450 purified from untreated rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Noninvasive tests of CYP3A enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Erythromycin breath test predicts oral clearance of cyclosporine in kidney transplant recipients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

First-pass metabolism of cyclosporin by the gut

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine*

7 January 2021

1 reference

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Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine*

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

From amplification to function: the case of the MDR1 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Biochemistry of multidrug resistance mediated by the multidrug transporter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Active transport of benzo[a]pyrene in apical membrane vesicles from normal human intestinal epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Clinical utility of breath tests for the assessment of hepatic function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

The erythromycin breath test selectively measures P450IIIA in patients with severe liver disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

P450 3A activity and cyclosporine dosing in kidney and heart transplant recipients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Cytochrome P450 of small intestinal epithelial cells. Immunochemical characterization of the increase in cytochrome P450 caused by phenobarbital

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Monoclonal antibodies against human liver cytochrome P-450

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Structure and expression of the human MDR (P-glycoprotein) gene family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Localization of villin, a cytoskeletal protein specific to microvilli, in human ileum and colon and in colonic neoplasms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

First-pass metabolism of midazolam by the human intestine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase I trial to modulate multidrug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Phase I and pharmacokinetic study of the multidrug resistance modulator dexverapamil with EPOCH chemotherapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Phase I study of etoposide with SDZ PSC 833 as a modulator of multidrug resistance in patients with cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Inhibition of intestinal P-glycoprotein and effects on etoposide absorption.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2897%2990027-8

10.1016/S0009-9236(97)90027-8

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9333100%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference