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English
Evidence that FTY720 induces T cell apoptosis in vivo
scientific article published on 01 June 2000
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
title
Evidence that FTY720 induces T cell apoptosis in vivo
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
main subject
apoptotic process
1 reference
based on heuristic
inferred from title
author name string
Y Nagahara
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
S Enosawa
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
M Ikekita
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
S Suzuki
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
T Shinomiya
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
publication date
1 June 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Immunopharmacology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
48
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
75-85
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
cites work
Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in chinese hamster ovary cell cultures treated with cisplatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of methods based on annexin-V binding, DNA content or TUNEL for evaluating cell death in HL-60 and adherent MCF-7 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of selective cell death targeting on mature T-lymphocytes in rats by a novel immunosuppressant, FTY720
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent immunosuppressants, 2-alkyl-2-aminopropane-1,3-diols
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Simple compounds, 2-alkyl-2-amino-1,3-propanediols have potent immunosuppressive activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c-mediated apoptosis in cells lacking mitochondrial DNA. Signaling pathway involving release and caspase 3 activation is conserved
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic and biochemical studies on the activation and cytotoxic mechanism of bredinin, a potent inhibitor of purine biosynthesis in mammalian cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The immunosuppressive potency in vitro of physiological and synthetic steroids on lymphocyte cultures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Labelling DNA strand breaks with BrdUTP. Detection of apoptosis and cell proliferation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the mode of action of a novel immunosuppressant FTY720 in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new immunosuppressant, FTY720, prolongs limb allograft survival in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies of the induction and maintenance of long-term graft acceptance by treatment with FK506 in heterotopic cardiac allotransplantation in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclophilin binds to the region of cyclosporine involved in its immunosuppressive activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early redistribution of plasma membrane phosphatidylserine during apoptosis of adult rat ventricular myocytes in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclosporin A, a Peptide Metabolite from Trichoderma polysporum (Link ex Pers.) Rifai, with a remarkable immunosuppressive activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel immunosuppressant, FTY720, increases the efficiency of a superantigen-induced peripheral T-cell deletion whilst inhibiting negative selection in the thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An immunosuppressive agent, FTY720, increases intracellular concentration of calcium ion and induces apoptosis in HL-60
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The in vivo induction of lymphocyte apoptosis in MRL-lpr/lpr mice treated with FTY720
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of azathioprine (Imuran) on the cell cycle of promonocytes and the production of monocytes in the bone marrow
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunosuppressive effects of FTY720 alone or in combination with cyclosporine and/or sirolimus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of a new immunosuppressive agent, FTY720, on survival of islet allografts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900181-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0162-3109(00)00181-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed publication ID
10822091
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10822091
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10822091%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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